(4-Carbamoyl-2-methoxyphenyl) nonanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: (4-Carbamoyl-2-methoxyphenyl) nonanoate
• 化学式: C₁₇H₂₅NO₄
• 分子量: 307.4
• InChiKey: ZANSQIXKDAUFJI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  78.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• FLAVOR COMPOSITION CONTAINING FLAVONE GLYCOSIDES
  申请人：Bardsley Kathryn

  公开号：US20120251465A1

  公开（公告）日：2012-10-04

  The present invention has discovered that flavone glycosides represented by Formula I set forth below have unexpected and advantageous flavor enhancement and modification properties: wherein R 1 is selected from the group consisting of H and CH 3 , R 2 is selected from the group consisting of H and OH, and R 3 is a 7-O-glycoside. Thus, the flavone glycosides of the present invention can be used to enhance or modify the flavor of orally consumable compositions, such as foodstuff, chewing gums, dental and oral hygiene products, and medicinal products.

  本发明发现了以下公式I所表示的黄酮苷具有意外和优越的口味增强和修改特性：其中R1选择自H和CH3的群组，R2选择自H和OH的群组，R3是7-O-糖苷。因此，本发明的黄酮苷可用于增强或修改口服组合物的口味，如食品、口香糖、口腔卫生产品和药品。
• [EN] PREPARATION AND PURIFICATION OF SYNTHETIC CAPSAICIN<br/>[FR] PREPARATION ET PURIFICATION DE CAPSICINE SYNTHETIQUE
  申请人：ALGORX PHARMACEUTICALS INC

  公开号：WO2004092122A2

  公开（公告）日：2004-10-28

  The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.

  本发明提供了一种合成辣椒素的反式异构体和/或类辣椒素化合物的方法，该方法利用一种过程，在合成反应的开始就设置了反式几何构型，并在整个合成过程中保持不变。
• Preparation and purification of synthetic capsaicin
  申请人：Chen Wei

  公开号：US20050085652A1

  公开（公告）日：2005-04-21

  The present invention provides methods for synthesizing the trans isomer of capsaicin and/or capsaicin-like compounds by utilizing a process wherein the trans geometry is set from the beginning of the synthesis reaction and carried through the entire synthesis process.

  本发明提供了一种合成辣椒素的反式异构体和/或类辣椒素化合物的方法，通过利用一种过程，其中从合成反应的开始就设置了反式几何结构，并贯穿整个合成过程。
• Pharmaceutical formulation containing bittering agent
  申请人：——

  公开号：US20030064099A1

  公开（公告）日：2003-04-03

  Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of a bittering agent to impart a bitter taste to an abuser upon administration of said dosage form after tampering.

  某些实施例中披露了一种口服剂型，其包括一种易于滥用的药物的治疗有效量；以及一种苦味剂的有效量，在篡改后使用该剂型时使滥用者感到苦味。
• Pharmaceutical formulation containing irritant
  申请人：——

  公开号：US20030068370A1

  公开（公告）日：2003-04-10

  Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of an irritant to impart an irritating sensation to an abuser upon administration of said dosage form after tampering.

  在某些实施例中，披露了一种口服剂型，该剂型包括一种易受滥用的治疗有效量药物；以及一种有效量的刺激剂，用于在篡改后给予滥用者在给药后产生刺激感。