3-(Furan-2-yl)-6-methyl-4-(4-methylsulfonylphenyl)pyran-2-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(Furan-2-yl)-6-methyl-4-(4-methylsulfonylphenyl)pyran-2-one
• 化学式: C₁₇H₁₄O₅S
• 分子量: 330.4
• InChiKey: MLDBVXBXFCLVEA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  82
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] 4-PHENYLPYRAN-2-ONE DERIVATIVES<br/>[FR] DERIVES DE 4-PHENYLPYRAN-2-ONE
  申请人：ALMIRALL PRODESFARMA SA

  公开号：WO2003006451A1

  公开（公告）日：2003-01-23

  The invention relates to 4-phenylpyran-2-one derivatives of formula (I) or pharmaceutically acceptable salts thereof, which are inhibitors of cyclooxygenase-2; to processes and intermediates for their preparation; to pharmaceutical compositions containing them; and to their use in the treatment or prevention of pathological conditions mediated by cyclooxygenase-2.