(2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (2S)-2-[4-(3-azidophenyl)-2-oxopyrrolidin-1-yl]butanamide
• 化学式: C14H17N5O2
• 分子量: 287.32
• InChiKey: HJTWBNCCSFVTLK-KFJBMODSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  77.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their use
  申请人：UCB S.A.

  公开号：EP1577296A1

  公开（公告）日：2005-09-21

  The invention concerns (2S)-2-[4-(2,2-difluoroviny)-2-oxopyrrolidin-1-yl]butanoic acid and stereoisomers thereof.

  本发明涉及(2S)-2-[4-(2,2-二氟乙烯基)-2-氧代吡咯烷-1-基]丁酸及其立体异构体。
• 2-Oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
  申请人：Differding Edmond

  公开号：US20050171188A1

  公开（公告）日：2005-08-04

  The invention concerns 2-oxo-1-pyrrolidine derivatives of formula I, wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.

  本发明涉及式I的2-氧代-1-吡咯烷衍生物，其中取代基如规范中所定义，以及它们作为药物的用途。本发明的化合物特别适用于治疗癫痫等神经系统疾病。
• 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses
  申请人：——

  公开号：US20030120080A1

  公开（公告）日：2003-06-26

  The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.

  本发明涉及式（I）的2-氧代-1-吡咯烷衍生物，其中取代基如规范中定义的那样，以及它们作为药物的用途。本发明的化合物特别适用于治疗癫痫等神经系统疾病。
• [EN] 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES<br/>[FR] DERIVES DE 2-OXO-1-PYRROLIDINE, PROCEDES DE PREPARATION ET UTILISATIONS DESDITS DERIVES
  申请人：UCB SA

  公开号：WO2001062726A2

  公开（公告）日：2001-08-30

  The invention concerns 2-oxo-1-pyrrolidine derivatives of formula (I) wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention are particularly suited for treating neurological disorders such as epilepsy.

  本发明涉及式（I）的2-氧代-1-吡咯烷衍生物，其中取代基如规范中所定义，以及它们作为药物的用途。本发明的化合物特别适用于治疗癫痫等神经系统疾病。
• Imidazole derivatives, processes for preparing them and their uses
  申请人：Kenda Benoit

  公开号：US20050137241A1

  公开（公告）日：2005-06-23

  The present invention relates to imidazole derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.

  本发明涉及咪唑衍生物，制备它们的方法，含有它们的制药组合物以及它们作为药物的用途。