1-(4-fluorophenyl)-1-(3-piperidin-1-ylpropyl)-3H-2-benzofuran-5-carbonitrile

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(4-fluorophenyl)-1-(3-piperidin-1-ylpropyl)-3H-2-benzofuran-5-carbonitrile
• 化学式: C₂₃H₂₅FN₂O
• 分子量: 364.5
• InChiKey: QOKYGVICHNDZAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] ISOBENZOFURAN DERIVATIVES<br/>[FR] DERIVES D'ISOBENZOFURANE
  申请人：RANBAXY LAB LTD

  公开号：WO2003042202A1

  公开（公告）日：2003-05-22

  The present invention relates to certain isobenzofuran derivatives and to a process for the synthesis of the same. The compounds of the present invention are analogs of a well known potent anti-depressant drug citalopram and hold promise to have anti-depressant activity. The invention also relates to pharmaceutical compositions containing the compounds of the present invention as potential anti-depressants.