2-[2-[2-(2-Hydroxyethoxy)phenyl]sulfonylphenoxy]ethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[2-[2-(2-Hydroxyethoxy)phenyl]sulfonylphenoxy]ethanol
• 化学式: C₁₆H₁₈O₆S
• 分子量: 338.4
• InChiKey: FKJVXIDKLHFJJR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Novel polyester, adhesives comprising it, and laminates made of it
  申请人：KURARAY CO., LTD.

  公开号：EP0112718A1

  公开（公告）日：1984-07-04

  A polyester containing aluminium atoms and monocarboxylic acid residues comprising constituent residues represented by the following formulas (I), (II), (III) and (IV): where Ri, in its repeated occurrence in the polyester, represents one or more bivalent groups each derived by removal of both carboxyl groups from terephthalic acid, isophthalic acid, orthophthalic acid or a straight-chained C4-10 aliphatic dicarboxylic acid; R2, in its repeated occurrence in the polyester, represents one or more univalent groups derived by removal of the carboxyl group from, a CB-30 aliphatic or alicyclic monocarboxylic acid or C7-20 aromatic monocarboxylic acid; D, in its repeated occurrence in the polyester, represents one or more bivalent groups each derived by removal of both hydroxyl groups from a C2-10 aliphatic diol or a C6-8 alicyclic diol; and each of m, n, p1, p2, p3 and q is 0 or 1, the constituent residues being bonded together in the combinations (I)-(II), (I)-(III), (II)-(III), (II)-(IV), (III)-(III) and (III)-(IV) and via only one oxygen atom in each combination, the molar ratio (I):(II) being substantially 1:1, the molar ratio (I):(III) being in the range 1,000:1 to 100:5 and the molar ratio (III):(IV) being in the range 4:1 to 1:10, the polyester having an intrinsic viscosity of not less than 0.5 dl/g is excellent in adhesibility and can be used inter alia as an adhesive. Using the polyester as an adhesive or a base, laminates and laminated hollow vessels comprising the polyester and an ethylene-vinyl alcohol copolymer can be produced. The laminates and laminated hollow vessels are suited for use inter alia as packaging materials or containers for food and drink.

  一种含有铝原子和单羧酸残基的聚酯，其组成残基由以下式子(I)、(II)、(III) 和(IV)表示： 其中，Ri，在聚酯中重复出现时，代表一个或多个二价基团，每个基团都是从对苯二甲酸、间苯二甲酸、邻苯二甲酸或直链 C4-10 脂肪族二羧酸中去除两个羧基而得到的；R2，在聚酯中重复出现时，代表一个或多个一价基团，这些基团是从 CB-30 脂肪族或脂环族一元羧酸或 C7-20 芳香族一元羧酸中去除羧基而得到的；在聚酯中重复出现的 D 代表一个或多个二价基团，每个二价基团通过从 C2-10 脂肪族二元醇或 C6-8 脂环族二元醇中去除两个羟基而衍生；m、n、p1、p2、p3 和 q 中的每一个均为 0 或 1，组成残基以 (I)-(II)、(I)-(III)、(II)-(III)、(II)-(IV)、(III)-(III) 和 (III)-(IV) 的组合键合在一起，且在每个组合中仅通过一个氧原子，摩尔比 (I)：(II)基本上为 1:1，摩尔比(I):(III)在 1,000:1 至 100:5 的范围内，摩尔比(III):(IV)在 4:1 至 1:10 的范围内，本征粘度不小于 0.5 dl/g 的聚酯具有优异的粘合性，可用作粘合剂等。使用聚酯作为粘合剂或基料，可以生产由聚酯和乙烯-乙烯醇共聚物组成的层压板和层压空心容器。这种层压板和层压中空容器特别适合用作食品和饮料的包装材料或容器。
• Polyester carbonate copolymers processes for preparing same and polyester resin compositions containing said copolymers
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0347169A2

  公开（公告）日：1989-12-20

  In accordance with the present invention, there are provided polyester carbonate copolymers obtained by polymerization of a mixture of 20-80% by weight of an alkylene terephthalate oligomer [I] containing ethylene terephthalate as main structural units and having an intrinsic viscosity [η], as measured at 25oC in o-­chlorophenol, of less than 0.6 dl/g, and 20-80% by weight of a carbonate oligomer [II] containing 2,2-bis(4-­hydroxyphenyl)propane as main structural units and having an intrinsic viscosity [η], as measured at 25oC in o-­chlorophenol, of less than 0.6 dl/g, said copolymers having an intrinsic viscosity [η], as measured at 25oC in o-chlorophenol, of 0.4-1.2 dl/g and a glass transition temperature (Tg) of 80-140oC with a single peak, and polyester resin compositions containing said copolymers, said resin composition being excellent in transparency, heat resistance and mechanical strength.

  根据本发明，提供了碳酸酯聚酯共聚物，该共聚物是由 20-80%（重量）的对苯二甲酸乙二醇酯低聚物[I]（含对苯二甲酸乙二醇酯作为主要结构单元）和 20-80%（重量）的碳酸酯低聚物[II]（含 2，2-双（4-羟基苯基）丙烷作为主要结构单元）的混合物聚合而成，碳酸酯低聚物[I]在 25oC 邻氯苯酚中测得的固有粘度[η]小于 0.6 dl/g，以及 20-80% （重量百分比）的碳酸酯低聚物 [II]，该低聚物含有 2,2-双（4-羟基苯基）丙烷作为主要结构单元，且在 25oC 时以邻氯苯酚计的固有粘度 [η]小于 0.6 dl/g，所述共聚物在 25oC 时以邻氯苯酚计的固有粘度 [η]为 0.4-1.2 dl/g，玻璃化转变温度 (Tg) 为 80-140oC 且只有一个峰值，以及含有所述共聚物的聚酯树脂组合物，所述树脂组合物具有优异的透明度、耐热性和机械强度。
• Percutaneous absorption-type pharmaceutical preparations
  申请人：NITTO DENKO CORPORATION

  公开号：EP1759693A2

  公开（公告）日：2007-03-07

  A percutaneous absorption-type pharmaceutical preparation containing a sublimation drug is provided, where from a plaster layer, a drug is released as volatile substance with a lapse of time, but the released drug has no adverse effect on the handling of the preparation, and the quality of the preparation is maintained in storage over a long period of time. A percutaneous absorption-type pharmaceutical preparation, which comprises: a support comprising a plastic film and a nonwoven fabric; and a plaster layer containing a sublimation drug, wherein the plastic film and the nonwoven fabric are laminated with an adhesive having a glass transition temperature of 10°C or higher, and the plaster layer is laminated on opposite side of the plastic film surface that the nonwoven fabric is laminated with.

  本发明提供了一种含有升华药物的经皮吸收型药物制剂，在该制剂中，随着时间的推移，药物会以挥发性物质的形式从石膏层中释放出来，但释放出来的药物不会对制剂的操作产生不良影响，并且在长期储存的情况下，制剂的质量可以保持不变。一种经皮吸收型药物制剂，它包括：由塑料薄膜和无纺布组成的支架；以及含有升华药物的膏药层，其中塑料薄膜和无纺布用玻璃化温度为 10°C 或更高的粘合剂层压，膏药层层压在与无纺布层压的塑料薄膜表面相反的一侧。
• Patch preparation
  申请人：NITTO DENKO CORPORATION

  公开号：EP2548551A1

  公开（公告）日：2013-01-23

  The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 µm to 16 µm; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.

  本发明提供了一种具有极低透湿性、足够的 ODT 效果、优异的药物释放性及其含药压敏胶层的锚定性，并具有优选贴片感觉的贴片制剂。本发明的贴片制剂包括一个支撑体；和一个压敏胶层，在支撑体的一个表面上含有粘附聚合物和药物，其中：支撑体按所述顺序具有聚酯基底层、无机氧化物层和聚酯无纺布层；聚酯基底层的厚度为 1.0 µm 至 16 µm；压敏胶层层压在聚酯无纺布层上。
• A patch comprising a three layer support
  申请人：NITTO DENKO CORPORATION

  公开号：EP2702968A1

  公开（公告）日：2014-03-05

  The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability, and has a preferred handleability. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1. 0 µm to 16 µm; and the pressure-sensitive adhesive layer is laminated on the polyester base layer.

  本发明提供了一种具有极低透湿性、足够的 ODT 效果、优异的药物释放性和优选的可操作性的贴片制剂。本发明的贴片制剂包括支撑物；以及在支撑物的一个表面上含有粘附聚合物和药物的压敏胶层，其中：支撑物按所述顺序具有聚酯基底层、无机氧化物层和聚酯无纺布层；聚酯基底层的厚度为 1.0 µm 至 16 µm；压敏胶层层压在聚酯基底层上。