4-Vinyl-n-hexylpyridinium bromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 4-Vinyl-n-hexylpyridinium bromide
• 英文别名: 4-ethenyl-1-hexylpyridin-1-ium;bromide
• 化学式: C13H20BrN
• 分子量: 270.21
• InChiKey: IGCDKCMEOZGINK-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  3.9
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• Method for Treating Surfaces with Copolymers
  申请人：Bouloussa Othman

  公开号：US20080226585A1

  公开（公告）日：2008-09-18

  The present invention relates to a method for treating at least a surface of a substrate containing labile hydrogen atoms to confer to it cytotoxic properties or cell-adhesion properties, characterized in that it comprises at least a step consisting of exposing, within a liquid medium, said substrate or a surface thereof with at least a copolymer, said copolymer containing at least a monomer unit of type A including at least a reactive site able to attach to said substrate or said surface by covalent bonds and at least a monomer unit of type B including at least one molecule able to confer antimicrobial, antiviricidal and/or antifungicidal or cell-adhesion properties to said substrate or said surface, said step being carried out in efficient conditions to promote the covalent grafting of said copolymer to said substrate or a surface thereof.

  本发明涉及一种处理含有不稳定氢原子的衬底表面的方法，以赋予其细胞毒性或细胞粘附性能。其特征在于，该方法包括至少一步，其中在液体介质中暴露该衬底或其表面至少一种共聚物，该共聚物包含至少一种A型单体单元，包括至少一种反应位点，能够通过共价键连接到该衬底或该表面，以及至少一种B型单体单元，包括至少一种分子，能够赋予该衬底或该表面抗微生物、抗病毒和/或抗真菌性能或细胞粘附性能，该步骤在有效条件下进行，以促进该共聚物与该衬底或其表面的共价嫁接。
• Antimicrobial polymeric surfaces
  申请人：——

  公开号：US20030091641A1

  公开（公告）日：2003-05-15

  Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.

  本发明公开了一种包含在材料上固定的聚合物化合物的杀菌组合物。还公开了包括这种杀菌组合物的医疗器械。公开了用抗菌聚阳离子，例如聚（乙烯基-N-吡啶溴化物）共价衍生化常见材料表面的方法；该方法的第一步涉及在表面上涂覆一层纳米硅。以这种方式衍生化的各种商业合成聚合物具有杀菌作用，即它们能够在接触时杀死沉积的革兰氏阳性和革兰氏阴性细菌，无论是通过空气还是水沉积。
• Method for treating surfaces with copolymers
  申请人：Institut Curie

  公开号：EP1707601A1

  公开（公告）日：2006-10-04

  The present invention relates to a method for treating at least a surface of a substrate containing labile hydrogen atoms to confer to it cytotoxic properties or cell-adhesion properties, characterized in that it comprises at least a step consisting of exposing, within a liquid medium, said substrate or a surface thereof with at least a copolymer, said copolymer containing at least a monomer unit of type A including at least a reactive site able to attach to said substrate or said surface by covalent bonds and at least a monomer unit of type B including at least one molecule able to confer antimicrobial, antiviricidal and/or antifungicidal or cell-adhesion properties to said substrate or said surface, said step being carried out in efficient conditions to promote the covalent grafting of said copolymer to said substrate or a surface thereof.

  本发明涉及一种处理至少含有易溶氢原子的基质表面以赋予其细胞毒性特性或细胞粘附特性的方法，其特征在于该方法至少包括以下步骤：在液体介质中，使所述基质或其表面与至少一种共聚物接触、所述共聚物至少包含一个 A 型单体单元，其中至少包含一个可通过共价键附着在所述基底或表面上的反应位点，以及至少一个 B 型单体单元，其中至少包含一个可赋予所述基底或表面抗微生物、抗病毒和/或抗真菌或细胞粘附特性的分子，所述步骤在有效条件下进行，以促进所述共聚物与所述基底或表面的共价接枝。
• EP1390158A4
  申请人：——

  公开号：EP1390158A4

  公开（公告）日：2004-06-09
• ANTIMICROBIAL POLYMERIC SURFACES
  申请人：MASSACHUSETTS INSTITUTE OF TECHNOLOGY

  公开号：EP1390158A1

  公开（公告）日：2004-02-25