(7R,7aS)-7-(3-cyclopentyloxy-4-methoxyphenyl)-7a-methyl-2,5,6,7-tetrahydro-1H-pyrrolo[1,2-c]imidazol-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (7R,7aS)-7-(3-cyclopentyloxy-4-methoxyphenyl)-7a-methyl-2,5,6,7-tetrahydro-1H-pyrrolo[1,2-c]imidazol-3-one
• 化学式: C₁₉H₂₆N₂O₃
• 分子量: 330.4
• InChiKey: CLPIVMFIGYRJRV-DNVCBOLYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.63
• 拓扑面积：
  50.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Methods of inducing ovulation using a non-polypeptide camp level modulator
  申请人：Palmer Stephen

  公开号：US20050148501A1

  公开（公告）日：2005-07-07

  The present invention relates to methods of inducing ovulation in a female host comprising the administration of a non-polypeptide cyclic adenosine monophosphate (cAMP) level modulator to female host. In another aspect, the invention provides for specific administration of the phosphodiesterase inhibitor prior to the luteal phase of the host's ovulatory cycle. Preferred non-polypeptide cAMP level modulator include phosphodiesterase inhibitors, particularly inhibitors of phosphodiesterase 4 isoforms.
• METHODS OF INDUCING OVULATION
  申请人：Palmer Stephen

  公开号：US20080293622A1

  公开（公告）日：2008-11-27

  The present invention relates to methods of inducing ovulation in a female host comprising the administration of a non-polypeptide cyclic adenosine monophosphate (cAMP) level modulator to the female host. In another aspect, the invention provides for specific administration of the phosphodiesterase inhibitor prior to the luteal phase of the host's ovulatory cycle. Preferred non-polypeptide cAMP level modulators include phosphodiesterase inhibitors, particularly inhibitors of phosphodiesterase 4 isoforms.
• US7078236B2
  申请人：——

  公开号：US7078236B2

  公开（公告）日：2006-07-18
• US7803760B2
  申请人：——

  公开号：US7803760B2

  公开（公告）日：2010-09-28