2-[[4-(4-Chlorophenyl)phenyl]-pyridin-4-ylmethyl]guanidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-[[4-(4-Chlorophenyl)phenyl]-pyridin-4-ylmethyl]guanidine
• 化学式: C₁₉H₁₇ClN₄
• 分子量: 336.8
• InChiKey: PUALIDJZNGMDCC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  77.3
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] METHODS OF TREATING DISEASE<br/>[FR] PROCEDES DE TRAITEMENT DE MALADIE
  申请人：SCION PHARMACEUTICALS INC

  公开号：WO2004071433A2

  公开（公告）日：2004-08-26

  The invention relates to substituted-guanidinyl compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of ion channel function, and treatment of disease and disease symptoms, particularly those mediated by certain calcium channel subtype targets.