{3-[4-(3-butyl-1-heptylureido)phenylsulphanyl]phenyl}acetic acid | 735274-20-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: {3-[4-(3-butyl-1-heptylureido)phenylsulphanyl]phenyl}acetic acid
• 英文别名: 2-[3-[4-[Butylcarbamoyl(heptyl)amino]phenyl]sulfanylphenyl]acetic acid
• CAS: 735274-20-1
• 化学式: C₂₆H₃₆N₂O₃S
• 分子量: 456.649
• InChiKey: MJVZDSRSJPEQSL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  32
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  94.9
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• [EN] COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS<br/>[FR] COMPOSES FONCTIONNANT COMME MODULATEURS DE RECEPTEURS DE TYPE PPAR ET LEUR UTILISATION DANS DES COMPOSITIONS COSMETIQUES OU PHARMACEUTIQUES
  申请人：GALDERMA RES & DEV

  公开号：WO2004072022A1

  公开（公告）日：2004-08-26

  The invention relates to novel compounds which correspond to the following general formula (I): their method of preparation, and their use in pharmaceutical compositions intended for use in human or veterinary medicine (in dermatology and in the field of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or in cosmetic compositions.

  该发明涉及与以下一般式（I）相对应的新化合物，它们的制备方法，以及它们在用于人类或兽医药物组合物中的用途（在皮肤病学和心血管疾病、免疫疾病和/或与脂质代谢相关的疾病领域），或者在化妆品组合物中的用途。
• Novel modulators of the PPAR-type receptors and cosmetic/pharmaceutical compositions comprised thereof
  申请人：Diaz Philippe

  公开号：US20060035969A1

  公开（公告）日：2006-02-16

  Novel compounds which modulate PPAR-type receptors have the following general formula (I): and are formulated into pharmaceutical compositions suited for administration in human or veterinary medicine (in dermatology and in the fields of cardiovascular diseases, immune diseases and/or diseases linked to lipid metabolism), or are formulated into cosmetic compositions.

  调节 PPAR 型受体的新型化合物具有以下通式 (I)： 并配制成适用于人类或兽医用药（皮肤病和心血管疾病、免疫疾病和/或与脂质代谢有关的疾病）的药物组合物，或配制成化妆品组合物。
• COMPOUNDS WHICH ARE MODULATORS OF THE PPAR-TYPE RECEPTORS AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
  申请人：Galderma Research & Development, S.N.C.

  公开号：EP1594837A1

  公开（公告）日：2005-11-16