4-Hydroxy-2-[3-(3-hydroxy-4-methoxyphenyl)propanoylamino]benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Hydroxy-2-[3-(3-hydroxy-4-methoxyphenyl)propanoylamino]benzoic acid
• 化学式: C₁₇H₁₇NO₆
• 分子量: 331.32
• InChiKey: JMIRHGOWIHVZFQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  24
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  116
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• Anthranilic acid amides and derivatives thereof as cosmetic and pharmaceutical agents
  申请人：Schmaus Gerhard

  公开号：US20060089413A1

  公开（公告）日：2006-04-27

  The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.

  式 1 的特定化合物（以及相应的混合物）的用途 以及相应的混合物，特别是用作化妆品剂，以抑制 P 物质诱导肥大细胞释放组胺。
• Antimicrobially active compounds for treating bad breath
  申请人：Rabenhorst Jurgen

  公开号：US20080008660A1

  公开（公告）日：2008-01-10

  The invention relates primarily to specific uses of a compound of the Formula 1 or of mixtures of two or more different compounds of the Formula 1, in particular for producing an antimicrobially acting agent and agent against bad breath, as well as the corresponding production methods. In addition the invention relates to specific products, in particular oral hygiene products, comprising or consisting of a compound of the Formula 1 or of a mixture of two or more different compounds of the Formula 1 wherein the radicals of the compound of the Formula 1 or of each compound of the Formula 1 in the mixture are as defined in the preceding description.
• MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING
  申请人：Schmaus Gerhard

  公开号：US20090226537A1

  公开（公告）日：2009-09-10

  The invention relates to a mixture comprising or consisting of: (a) one or more compounds of Formula 1: where the symbols in the compound or each compound of Formula 1 are defined as follows: m=0, 1, 2 or 3, p=0, 1 or 2, n=0, 1 or 2, where, when n=1 or 2, R 1 and R 2 in pairs are each H or together are another chemical bond, where, when m=1, 2 or 3, each X independently of the others is OH, O-alkyl or O-acyl, and where, when p=1 or 2, each Y independently of the others is OH, O-alkyl or O-acyl, and R 3 =H or alkyl, R 3 =H also representing the corresponding cosmetically or pharmaceutically acceptable salts and solvates; and (b) one or more antidandruff agents.
• Mixtures Comprising Anthranilic Acid Amides and Cooling Agents as Cosmetic and Pharmaceutical Compositions for Alleviating Itching
  申请人：Vielhaber Gabriele

  公开号：US20090297468A1

  公开（公告）日：2009-12-03

  The invention relates to a mixture comprising or consisting of: (a) one or more compounds of Formula 1: where the symbols in the compound or each compound of Formula 1 are defined as follows: m=0, 1, 2 or 3, p=0, 1 or 2, n=0, 1 or 2, where, when n=1 or 2, R 1 and R 2 in pairs are each H or together are another chemical bond, where, when m=1, 2 or 3, each X independently of the others is OH, Oalkyl or Oacyl, and where, when p=1 or 2, each Y independently of the others is OH, Oalkyl or Oacyl, and R 3 =H or alkyl, R 3 =H also representing the corresponding cosmetically or pharmaceutically acceptable salts and solvates; and (b) one or more cooling agents.
• ANTHRANILLIC ACID AMIDES AND DERIVATIVES THEREOF AS COSMETIC AND PHARMACEUTICAL ACTIVE COMPOUNDS
  申请人：Schmaus Gerhard

  公开号：US20120315233A1

  公开（公告）日：2012-12-13

  The use of specific compounds of the Formula 1 (and also corresponding mixtures) in particular as cosmetic agents for the inhibition of the substance P-induced release of histamine from mast cells is described.