4-(Dihydroxymethyl)benzoic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(Dihydroxymethyl)benzoic acid
• 化学式: C₈H₈O₄
• 分子量: 168.15
• InChiKey: OILLYEPVKNERHY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  77.8
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Modifying agent, polyamide copolymer synthesized using modifying agent and method for preparing polyamide copolymer
  申请人：National Taipei University of Technology

  公开号：US20190040197A1

  公开（公告）日：2019-02-07

  The invention provides a modifying agent, for synthesizing a polyamine copolymer, being a amide- group-containing diamine which is a reaction product of an aliphatic diamine and a first carboxylate, or a salt formed by reacting the amide- group-containing diamine with a second carboxylic acid, wherein the amide- group-containing diamine is represented by the general formula (I) where y represents an integer within 2˜6 (2 ≤y≤6) and x represents an integer within 4˜18 (4≤x≤18); the first carboxylate is an ester formed from an aliphatic carboxylic acid and the second carboxylic acid is a carboxylic acid.

  该发明提供了一种改性剂，用于合成聚胺共聚物，它是一种含酰胺基的二胺，是脂肪族二胺和第一羧酸盐的反应产物，或者是通过将含酰胺基的二胺与第二羧酸发生反应形成的盐，其中含酰胺基的二胺由一般式（I）表示，其中y表示2〜6之间的整数（2≤y≤6），x表示4〜18之间的整数（4≤x≤18）；第一羧酸盐是由脂肪族羧酸和第二羧酸形成的酯。
• [EN] METHOD OF PREPARING ESTERS OF TEREPHTHALIC ACID<br/>[FR] PROCÉDÉ DE PRÉPARATION D'ESTERS D'ACIDE TÉRÉPHTALIQUE
  申请人：SIBUR HOLDING PUBLIC JOINT STOCK CO

  公开号：WO2019066671A1

  公开（公告）日：2019-04-04

  The present invention relates to the field of preparing esters of terephthalic acid, used as plasticizers for the manufacture of plasticizers for polyvinyl chloride plastic materials. The invention discloses a method according to which the step of esterification of the acid with an alcohol comprises the use of two catalysts of different nature, in particular a metal-containing catalyst and an acid catalyst, which are added sequentially. The technical result of the present invention is to increase conversion of terephthalic acid up to 100% and to reduce the amount of by-products formed during the production of a dicarboxylic acid ester. The obtained ester is characterized by a low acid number and a low value of color.

  本发明涉及制备对苯二甲酸酯的领域，用于制造聚氯乙烯塑料材料的增塑剂。本发明公开了一种方法，其中酸与醇酯化的步骤包括使用两种不同性质的催化剂，特别是含金属催化剂和酸催化剂，这些催化剂是依次添加的。本发明的技术效果是提高对苯二甲酸的转化率达到100％，并减少在制备二羧酸酯时形成的副产物的量。所得的酯具有低酸值和低色值的特点。
• AMPHIPHILIC JANUS-DENDRIMERS
  申请人：Percec Virgil

  公开号：US20120308640A1

  公开（公告）日：2012-12-06

  The invention concerns compounds of the formula: X—(Y) t wherein: X is Formula (X), each Y is the same or different and is Formula (Y) —O—[CH 2 —CH(OH)—CH 2 —O—] m —H; or —C(OR 5 ) 3 ; R 1 , R 2 , R 3 , R 6 , R 7 , R 8 , R 9 , R 10 are each, independently, —(CH 2 CH 2 O) m —R 4 , —[CH 2 CH(OH)CH 2 O] n H, OR 11 , —O(CH 2 ) P R 13 , or —(CH 2 )R 12 ; each R 4 is independently OR 5 or OH; R 5 , R 11 and R 12 are each, independently, H or C 1 -C 30 alkyl; R 13 is —NH 3 + Cl − or —NHBoc; t is an integer from 2 to 6; m, n, and p are each, independently, an integer from 1 to 12; and each q, r, and s is 0 or 1 and the sum of q+r+s is at least 2.

  本发明涉及以下式的化合物：X—（Y）t其中：X是式（X），每个Y相同或不同，是式（Y）—O—[ —CH（OH）—CH2—O—]m—H；或—C（OR5）3；R1、R2、R3、R6、R7、R8、R9、R10各自独立地为—（ O）m—R4，—[ CH（OH） O]nH，OR11，—O（ ）PR13或—（ ）R12；每个R4独立地为OR5或OH；R5、R11和R12各自独立地为H或C1-C30烷基；R13为—NH3+Cl−或—NHBoc；t为2至6的整数；m、n和p各自独立地为1至12的整数；每个q、r和s为0或1，且q+r+s的总和至少为2。
• INDOLE DERIVATIVES AS 5-ALPHA-REDUCTASE-1-INHIBITORS
  申请人：Pfizer Limited

  公开号：EP0714390A1

  公开（公告）日：1996-06-05
• NOUVEAUX DERIVES AMPHIPHILES DE L ALPHA-C-PHENYL-N-TERT-BUTYL NITRONE
  申请人：TS Pharma

  公开号：EP1560837B1

  公开（公告）日：2009-08-05