1-hydroxyethyl-5-isopropyl-3-pentafluorophenyl-2-thiohydantoin

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 1-hydroxyethyl-5-isopropyl-3-pentafluorophenyl-2-thiohydantoin
• 英文别名: 1-(2-Hydroxyethyl)-3-(2,3,4,5,6-pentafluorophenyl)-5-propan-2-yl-2-sulfanylideneimidazolidin-4-one；1-(2-hydroxyethyl)-3-(2,3,4,5,6-pentafluorophenyl)-5-propan-2-yl-2-sulfanylideneimidazolidin-4-one
• 化学式: C₁₄H₁₃F₅N₂O₂S
• 分子量: 368.327
• InChiKey: NSPYFWPVXXHREE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  75.9
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  2-溴代异戊酸 在 碳酸氢钠 作用下， 以 丙醇 、 水 为溶剂， 反应 17.0h， 生成 1-hydroxyethyl-5-isopropyl-3-pentafluorophenyl-2-thiohydantoin
  参考文献：
  名称：

  Rydberg, Per; Luening, Bjoern; Wachtmeister, Carl Axel, Acta Chemica Scandinavica, 1993, vol. 47, # 8, p. 813 - 817

  摘要：

  DOI：

文献信息

• Method for analyzing n-terminal protein adducts
  申请人：Rydberg Per

  公开号：US20070190659A1

  公开（公告）日：2007-08-16

  Method for analyzing adducts in a fluid and/or a solid material suspected of containing the adducts by bringing the material in contact with an isothiocyanate reagent containing a fluorescent. The reagent do not have the isothiocyanate group directly bound to an unsubstituted phenyl or pentafluorophenyl group. A method for manufacturing a standard material for use in the analyzing method, a standard material obtainable by this manufacturing method. Compounds suitable for use as standard material and use of the standard material, and a container for analyzing the adducts are also disclosed. A method for analyzing hazardous substances, a kit including standard material or a compound set out above, an apparatus for performing the analyzing method, and a computer program stored on a data carrier for performing the analyzing method or the manufacturing method are also disclosed.

  一种分析液体和/或固体材料中可能含有的加合物的方法，通过将材料与含有荧光物的异硫氰酸酯试剂接触。该试剂不直接与未取代的苯基或五氟苯基结合的异硫氰酸酯基团。还公开了一种用于分析方法的标准材料制造方法，可获得此制造方法得到的标准材料。还公开了适用于作为标准材料的化合物以及标准材料的使用和用于分析加合物的容器。还公开了一种分析危险物质的方法，包括上述标准材料或化合物集的试剂盒，用于执行分析方法的设备以及存储在数据载体上的用于执行分析方法或制造方法的计算机程序。
• METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS
  申请人：Adduct Analys AB

  公开号：EP1738177A1

  公开（公告）日：2007-01-03
• US7718437B2
  申请人：——

  公开号：US7718437B2

  公开（公告）日：2010-05-18
• [EN] METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS<br/>[FR] PROCEDE D'ANALYSE DE COMPOSES D'ADDITIONS DE PROTEINES A TERMINAL N
  申请人：ADDUCT ANALYS AB

  公开号：WO2005101020A1

  公开（公告）日：2005-10-27

  The present invention provides a method for analyzing adducts in a fluid and/or a solid material suspected of containing said adducts by bringing said material in contact with an isothiocyanate reagent containing a fluorescent. Said reagent do not have the isothiocyanate group directly bound to an unsubstituted phenyl or pentafluorophenyl group. It also provides a method for manufacturing a standard material for use in said analyzing method. It also provides a standard material obtainable by said manufacturing method. It also provides compounds suitable for use as standard material and also use of a standard material. It also provides a container for use when analyzing adducts in a fluid or a solid material suspected of containing said adducted compounds. It also provides a method for analyzing hazardous substances. Further it also provides a kit comprising standard material or a compound set out above. It also provides an apparatus for performing the analyzing method. Further it also provides a computer program stored on a data carrier for performing the analyzing method or the manufacturing method set out above.
• Rydberg, Per; Luening, Bjoern; Wachtmeister, Carl Axel, Acta Chemica Scandinavica, 1993, vol. 47, # 8, p. 813 - 817
  作者：Rydberg, Per、Luening, Bjoern、Wachtmeister, Carl Axel、Toernqvist, Margareta

  DOI：——

  日期：——