threo-3,4-Diamino-hexan

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: threo-3,4-Diamino-hexan
• 英文别名: d,l-3,4-Diamino-hexan；(3R,4R)-hexane-3,4-diamine
• 化学式: C₆H₁₆N₂
• 分子量: 116.206
• InChiKey: IWCAQTQMDRGMPI-PHDIDXHHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  苯酐 、 threo-3,4-Diamino-hexan 以 丙酮 为溶剂， 生成 N--phthalsaeuremonoamid
  参考文献：
  名称：

  Pfordte,K.; Leuschner,G., Justus Liebigs Annalen der Chemie, 1961, vol. 646, p. 25 - 30

  摘要：

  DOI：
• 作为产物：
  描述：

  反-3-已烯 生成 threo-3,4-Diamino-hexan
  参考文献：
  名称：

  顺式和反式1,2-二氨基环己烷和脂肪族邻二胺的立体特异性合成。

  摘要：

  DOI：

  10.1021/jo01278a001

文献信息

• NOVEL FUSED-RING COMPOUND
  申请人：Ajinomoto Co., Inc.

  公开号：EP1707567A1

  公开（公告）日：2006-10-04

  The following fused polycyclic compound, analogues thereof or pharmaceutically acceptable salts thereof have an effect of increasing the sugar-transporting capacity and an effect of lowering the blood glucose level and, therefore, they are useful for preventing and/or treating diabetes and the like. wherein R is a methoxy group, Y is a (2-thiazolyl)-2-ethylcarbonyl group, R10 and R13 are hydrogen atoms, and R11 and R12 are methyl groups.

  下列融合多环化合物、其类似物或其药学上可接受的盐具有提高糖运输能力和降低血糖水平的作用，因此可用于预防和/或治疗糖尿病等。 其中 R 是甲氧基，Y 是（2-噻唑基）-2-乙基羰基，R10 和 R13 是氢原子，R11 和 R12 是甲基。
• Method of preparing poly(alkylene carbonate) via copolymerization of carbon dioxide/epoxide in the presence of novel complex
  申请人：SK Innovation Co., Ltd.

  公开号：US10723837B2

  公开（公告）日：2020-07-28

  Provided is a method of preparing poly(alkylene carbonate) using a molecular weight regulator in a process of preparing a copolymer of carbon dioxide/epoxide using a novel complex synthesized from salen-type ligand including a quaternary ammonium salt as a catalyst. According to the present invention, even though the molecular weight regulator is used, an activity of the catalyst may be stably maintained, whereby the low molecular weight of poly(alkylene carbonate) having a desirable level may be effectively provided. In addition, it is expected that since the novel complex as the catalyst of the present invention has a simple structure as compared to the existing copolymerization catalyst, due to the economical preparation cost thereof, the novel complex may be effectively applied to a large-scale commercial process.

  本发明提供了一种在制备二氧化碳/环氧化物共聚物的过程中使用分子量调节剂制备聚（碳酸亚烷基酯）的方法，该方法使用了一种由包括季铵盐的沙伦型配体合成的新型配合物作为催化剂。根据本发明，即使使用分子量调节剂，催化剂的活性仍可稳定保持，从而可有效提供具有理想水平的低分子量聚（碳酸亚烷基酯）。此外，由于作为本发明催化剂的新型络合物与现有的共聚催化剂相比结构简单，制备成本低廉，因此预计新型络合物可有效地应用于大规模商业工艺中。
• Fused polycyclic compounds
  申请人：Hirama Ryusuke

  公开号：US20060258637A1

  公开（公告）日：2006-11-16

  The following fused polycyclic compound, analogues thereof or pharmaceutically acceptable salts thereof have an effect of increasing the sugar-transporting capacity and an effect of lowering the blood glucose level and, therefore, they are useful for preventing and/or treating diabetes and the like. wherein R is a methoxy group, Y is a (2-thiazolyl)-2-ethylcarbonyl group, R 10 and R 13 are hydrogen atoms, and R 11 and R 12 are methyl groups.
• HETEROCYCLIC COMPOUNDS AS AXL INHIBITORS
  申请人：CHANGZHOU JIEKAI PHARMATECH CO., LTD.

  公开号：US20170137426A1

  公开（公告）日：2017-05-18

  Compounds of Formula I and their uses of effective AXL inhibitors and for the treatment of physical condition mediated by AXL.
• Method of Preparing Poly(Alkylene Carbonate) via Copolymerization of Carbon Dioxide/Epoxide in the Presence of Novel Complex
  申请人：SK Innovation Co., Ltd.

  公开号：US20180223042A1

  公开（公告）日：2018-08-09

  Provided is a method of preparing poly(alkylene carbonate) using a molecular weight regulator in a process of preparing a copolymer of carbon dioxide/epoxide using a novel complex synthesized from salen-type ligand including a quaternary ammonium salt as a catalyst. According to the present invention, even though the molecular weight regulator is used, an activity of the catalyst may be stably maintained, whereby the low molecular weight of poly(alkylene carbonate) having a desirable level may be effectively provided. In addition, it is expected that since the novel complex as the catalyst of the present invention has a simple structure as compared to the existing copolymerization catalyst, due to the economical preparation cost thereof, the novel complex may be effectively applied to a large-scale commercial process.