diphenylmethane dicarbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diphenylmethane dicarbamate
• 英文别名: methyl N-[2-[[2-(methoxycarbonylamino)phenyl]methyl]phenyl]carbamate
• 化学式: C₁₇H₁₈N₂O₄
• 分子量: 314.341
• InChiKey: WOVJZPCUZYNKBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 N-苯基香豆甲酯 在 盐酸 作用下， 以 水 为溶剂， 反应 2.0h， 以98%的产率得到diphenylmethane dicarbamate
  参考文献：
  名称：

  由苯氨基甲酸酯合成二苯甲烷二氨基甲酸酯 的方法

  摘要：

  由苯氨基甲酸酯合成二苯甲烷二氨基甲酸酯的方法，以苯氨基甲酸酯、碳酸二甲酯、亚甲基化试剂原料，无机酸作为催化剂，一步合成二苯甲烷二氨基甲酸酯。本发明解决了制备二苯甲烷二氨基甲酸酯过程中原料转化率低、产物产率低、选择性差等问题，反应后产物分离提纯操作简便、剩余反应液可循环利用。本方法如下：将苯氨基甲酸酯、无机酸催化剂、溶剂碳酸二甲酯加入到反应器中，加热升温，待苯氨基甲酸酯溶解后加入亚甲基化试剂，控制温度在50‑150℃之间反应0.1‑10 h，反应完成后冷却，过滤、水洗、干燥，得到产物二苯甲烷二氨基甲酸酯，产率达95%以上，原料转化率为98%以上。

  公开号：

  CN107434774B

文献信息

• PROCESS FOR PRODUCING POLYURETHANE
  申请人：DAICEL CHEMICAL INDUSTRIES, LTD.

  公开号：EP0477376A1

  公开（公告）日：1992-04-01

  A process for producing polyurethane useful as coating material, which comprises preparing dialkyl carbonate substantially without using phosgene, reacting the carbonate with a diamine to give a urethane, thermally decomposing it into a diisocyanate, and converting it into a polyurethane in the presence of a Lewis acid and/or a protonic acid. The reaction of a diisocyanate compound containing a reduced amount of chlorine is promoted by a Lewis acid and/or a protonic acid.

  一种生产用作涂层材料的聚氨酯的工艺，包括基本不使用光气制备碳酸二烷基酯，使碳酸酯与二胺反应生成聚氨酯，热分解成二异氰酸酯，并在路易斯酸和/或质子酸存在下转化成聚氨酯。路易斯酸和/或质子酸可促进含氯量降低的二异氰酸酯化合物的反应。
• METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYAMINO FORMATE
  申请人：Institute of Process Engineering, Chinese Academy of Sciences

  公开号：EP2752405A1

  公开（公告）日：2014-07-09

  A method for preparing polymethylene polyphenyl polycarbamate is provided, which is carried out through the condensation of phenylcarbamate with a methylating reagent under the catalyzation of a phase transfer acid catalyst. The method comprises: dissolving phenylcarbamate in a water-immiscible organic solvent to form a solution A; formulating an aqueous acid catalyst solution to form a solution B; forming a reaction system comprising an organic phase and an aqueous phase by firstly adding a methylating reagent to the solution B and then mixing the solution A and the solution B or by adding the methylating reagent at the same time of mixing the solution A and the solution B or after mixing the solution A and the solution B; reacting the reaction system under stirring at a reaction temperature of 30°C to 200°C and a reaction pressure of 0.05MPa to 5MPa; and separating a polymethylene polyphenyl polycarbamate product mixture by allowing the organic phase and the aqueous phase to stand still and stratify. The method can realize the high selectivity and yield of the product and is easy to separate the product.

  本发明提供了一种制备聚亚甲基聚苯基聚氨基甲酸酯的方法，该方法是在相转移酸催化剂的催化下，通过苯基氨基甲酸酯与甲基化试剂的缩合来实现的。该方法包括将苯基氨基甲酸酯溶解在不溶于水的有机溶剂中，形成溶液 A； 配制酸催化剂水溶液，形成溶液 B；先在溶液 B 中加入甲基化试剂，然后混合溶液 A 和溶液 B，或在混合溶液 A 和溶液 B 的同时加入甲基化试剂，或在混合溶液 A 和溶液 B 之后加入甲基化试剂，形成包括有机相和水相的反应体系；在搅拌下，在反应温度为 30°C 至 200°C 和反应压力为 0.05MPa 至 5MPa；通过使有机相和水相静止并分层，分离出聚亚甲基聚苯基聚氨基甲酸酯产品混合物。该方法可实现产品的高选择性和高产率，且易于分离产品。
• PROCESS FOR THE PREPARATION OF N-SUBSTITUTED CARBAMIC ACID ESTER AND PROCESS FOR THE PREPARATION OF ISOCYANATE USING THE N-SUBSTITUTED CARBAMIC ACID ESTER
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP2322504B9

  公开（公告）日：2017-09-06
• N-Substituted Carbamic Acid Ester Production Method and Isocyanate Production Method Using the N-Substituted Carbamic Acid Ester
  申请人：Miyake Nobuhisa

  公开号：US20110160476A1

  公开（公告）日：2011-06-30

  The present invention provides a method for producing N-substituted carbamic acid-O-aryl ester derived from a compound having an ureido group, the method comprising the step of carrying out esterification or esterification and transesterification from the compound having the ureido group and a hydroxy composition containing one type or a plurality of types of hydroxy compounds.
• METHOD FOR PREPARING POLYMETHYLENE POLYPHENYL POLYCARBAMATE
  申请人：Li Huiquan

  公开号：US20140316100A1

  公开（公告）日：2014-10-23

  A method for preparing polymethylene polyphenyl polycarbamate is provided, which is carried out through the condensation of phenylcarbamate with a methylating reagent under the catalyzation of a phase transfer acid catalyst. The method comprises: dissolving phenylcarbamate in a water-immiscible organic solvent to form a solution A; formulating an aqueous acid catalyst solution to fibrin a solution B; forming a reaction system comprising an organic phase and an aqueous phase by firstly adding a methylating reagent to the solution B and then mixing the solution A and the solution B or by adding the methylating reagent at the same time of mixing the solution A and the solution B or after mixing the solution A and the solution B; reacting the reaction system under stirring at a reaction temperature of 30° C. to 200° C. and a reaction pressure of 0.05 MPa to 5 MPa; and separating a polymethylene polyphenyl polycarbamate product mixture by allowing the organic phase and the aqueous phase to stand still and stratify. The method can realize the high selectivity and yield of the product and is easy to separate the product.