1-Phenyltriaza-1,2-dien-2-ium

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Phenyltriaza-1,2-dien-2-ium
• 英文别名: imino(phenylimino)azanium
• 化学式: C6H6N3+
• 分子量: 120.13
• InChiKey: YEUMQBKLOSWNSD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.87
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] RADIOIODINATED TROPANE DERIVATIVES<br/>[FR] DÉRIVÉS DE TROPANE RADIO-IODÉS
  申请人：GE HEALTHCARE LTD

  公开号：WO2011076778A1

  公开（公告）日：2011-06-30

  The present invention provides novel radio iodinated tropanes incorporating triazole or isoxazole rings. Also provided are methods of preparation of said tropanes from functionalised tropane precursors, using click cycloaddition chemistry, as well as radiopharmaceutical compositions comprising such radio iodinated tropanes. The invention also provides in vivo imaging methods using the radio iodinated tropanes.

  本发明提供了包含三唑或异噁唑环的新型放射性碘化曲脱品。还提供了从功能化曲脱前体制备所述曲脱品的方法，使用点击环加成化学，以及包含这种放射性碘化曲脱品的放射性药物组合物。该发明还提供了使用这种放射性碘化曲脱品的体内成像方法。
• IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION
  申请人：Bristol-Myers Squibb Company

  公开号：EP2841437B1

  公开（公告）日：2017-07-05
• IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION
  申请人：BRISTOL-MYERS SQUIBB COMPANY

  公开号：US20170247395A1

  公开（公告）日：2017-08-31

  The present invention provides thiazole compounds of Formula I wherein W, Y, R 0 , R 2 , R 4 , R 5 , R 6 , R 7 , X 1 , X 2 , X 3 and X 4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
• US9605024B2
  申请人：——

  公开号：US9605024B2

  公开（公告）日：2017-03-28
• US9688695B2
  申请人：——

  公开号：US9688695B2

  公开（公告）日：2017-06-27