A composition for forming a polymeric cell culture surface includes (i) a pre-polymer comprising a polymer backbone, a cationic moiety conjugated to the backbone, and a cross-linker moiety conjugated to the backbone; and (ii) a peptide-polymer comprising a polymer backbone and cell adhesive peptide conjugated to the backbone. Cross-linked coatings for cell culture that have a suitable amount of cell adhesive peptide and cationic moiety may be formed from the pre-polymer and peptide-polymer.
一种用于形成聚合
细胞培养表面的组合物包括(i)预聚合物,其包括聚合物骨架,与骨架共轭的阳离子基团和与骨架共轭的
交联剂基团;和(ii)肽聚合物,其包括聚合物骨架和细胞黏附肽共轭到骨架上。预聚合物和肽聚合物可以形成适量细胞黏附肽和阳离子基团的交联涂层,用于
细胞培养。