2-diphenylphosphino-1-phenyl-1-hexene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-diphenylphosphino-1-phenyl-1-hexene
• 英文别名: diphenyl-[(E)-1-phenylhex-1-en-2-yl]phosphane
• 化学式: C₂₄H₂₅P
• 分子量: 344.436
• InChiKey: ZOGNZYWWIAKQNQ-HIXSDJFHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  25
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  1-苯基-1-己炔 、 (tert-butyldimethylsilyl)diphenylphosphine 在 chloro(1,5-cyclooctadiene)rhodium(I) dimer silver trifluoromethanesulfonate 作用下， 以 甲醇 、 苯 为溶剂， 以72%的产率得到2-diphenylphosphino-1-phenyl-1-hexene
  参考文献：
  名称：

  烯基膦的区域和立体选择性合成：使用甲硅烷基膦的铑催化炔烃的加氢磷酸化

  摘要：

  描述了使用甲硅烷基膦作为膦基源的新型铑催化炔烃的加氢磷酸化反应。各种具有芳基，烷基和羧基的炔烃，包括末端和内部的炔烃，都以高度区域选择性和顺选择性的方式得到相应的烯基膦。具有吸电子基团的烯烃也以良好的产率得到相应的加合物。

  DOI：

  10.1021/jo061739f

文献信息

• Synthesis of Calcium and Ytterbium Complexes Supported by a Tridentate Imino-Amidinate Ligand and Their Application in the Intermolecular Hydrophosphination of Alkenes and Alkynes
  作者：Hongfan Hu、Chunming Cui

  DOI：10.1021/om201223j

  日期：2012.2.13

  r}MN(SiMe3)2}(THF)] (M = Ca, Yb; Ar = 2,6-iPr2C6H3) have been synthesized and characterized. They catalyze the intermolecular hydrophosphination of alkenes, dienes, and alkynes with high activity and selectivity under mild conditions. Highly selective 1,4-additions (94–100%) for the conjugated dienes examined have been observed with both catalysts. The calcium complex exclusively catalyzes anti addition

  明确定义的钙和络合物[2-NC（Ph）NArC 6 H 4 CHNAr} M N（SiMe 3）2 }（THF）]（M = Ca，Yb; Ar = 2,6- i Pr 2 C 6高3）已被合成和表征。它们在温和条件下以高活性和选择性催化烯烃，二烯和炔烃的分子间加氢磷酸化。在两种催化剂上均观察到对所检测的共轭二烯具有高选择性的1,4-加成（94-100％）。钙络合物专门催化向炔烃（包括末端炔烃）的反加成反应，而in在大多数情况下则催化顺式加成反应。钙催化剂可以在相对温和的条件下促进受阻烯烃（如二苯乙烯）的加氢磷酸化。
• Fluoride-mediated phosphination of alkenes and alkynes by silylphosphines
  作者：Minoru Hayashi、Yutaka Matsuura、Yutaka Watanabe

  DOI：10.1016/j.tetlet.2004.10.098

  日期：2004.12

  Regioselective phosphination of carbon-carbon unsaturated bonds by a fluoride-mediated reaction of silylphosphines is described. Alkenes and alkynes having a directing group, such as an aromatic or a carbonyl group, reacted to form a carbon-phosphorus bond under mild conditions. When an anhydrous fluoride source was applied in the presence of an electrophile, the corresponding three-component coupling product was obtained. (C) 2004 Elsevier Ltd. All rights reserved.
• Regio- and Stereoselective Synthesis of Alkenylphosphines:  A Rhodium-Catalyzed Hydrophosphination of Alkynes Using a Silylphosphine
  作者：Minoru Hayashi、Yutaka Matsuura、Yutaka Watanabe

  DOI：10.1021/jo061739f

  日期：2006.11.1

  A novel rhodium-catalyzed hydrophosphination of alkynes using a silylphosphine as a phosphino group source is described. A variety of alkynes, both terminal and internal ones with aryl, alkyl, and carboxyl groups, gave the corresponding alkenylphosphines in a highly regioselective and syn-selective manner. Alkenes with an electron-withdrawing group also gave the corresponding adducts in good yields

  描述了使用甲硅烷基膦作为膦基源的新型铑催化炔烃的加氢磷酸化反应。各种具有芳基，烷基和羧基的炔烃，包括末端和内部的炔烃，都以高度区域选择性和顺选择性的方式得到相应的烯基膦。具有吸电子基团的烯烃也以良好的产率得到相应的加合物。