piperonyl dibromide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: piperonyl dibromide
• 英文别名: 3,4-methylenedioxybenzal bromide；5-(Dibromomethyl)-1,3-benzodioxole
• 化学式: C₈H₆Br₂O₂
• 分子量: 293.942
• InChiKey: JCEFFRUGDXUMOY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  胡椒醛 在 亚磷酸三苯酯 、 溴 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以65%的产率得到piperonyl dibromide
  参考文献：
  名称：

  A Mild Synthesis of Vinyl Halides and gem-Dihalides Using Triphenyl Phosphite−Halogen-Based Reagents

  摘要：

  A new application of (PhO)(3)P-halogen-based reagents to the synthesis of vinyl halides and gem-dihalides is described. Vinyl halides were prepared in good to excellent yields from enolizable ketones, whereas aldehydes afforded the corresponding gem-dihalides. The halogenation proceeded smoothly under mild conditions.

  DOI：

  10.1021/jo061346g

文献信息

• Process for preparing aromatic aldehydes
  申请人：Sumitomo Chemical Company, Limited

  公开号：US04335263A1

  公开（公告）日：1982-06-15

  A process for preparing an aromatic aldehyde represented by the following general formula: ##STR1## wherein R.sub.1 and R.sub.2 each represents a hydrogen atom or a lower alkyl group or R.sub.1 and R.sub.2 may jointly form an alkylene group, provided that R.sub.1 and R.sub.2 do not represent a hydrogen atom at the same time.

  制备一种由以下通用式表示的芳香醛的方法：##STR1## 其中R.sub.1和R.sub.2分别代表氢原子或较低的烷基基团，或R.sub.1和R.sub.2可以共同形成一个烷基基团，前提是R.sub.1和R.sub.2不能同时代表氢原子。
• Process for preparing 3,4-substituted benzaldehydes
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0031253B1

  公开（公告）日：1983-10-05
• US4335263A
  申请人：——

  公开号：US4335263A

  公开（公告）日：1982-06-15
• A Mild Synthesis of Vinyl Halides and <i>gem</i>-Dihalides Using Triphenyl Phosphite−Halogen-Based Reagents
  作者：Alberto Spaggiari、Daniele Vaccari、Paolo Davoli、Giovanni Torre、Fabio Prati

  DOI：10.1021/jo061346g

  日期：2007.3.1

  A new application of (PhO)(3)P-halogen-based reagents to the synthesis of vinyl halides and gem-dihalides is described. Vinyl halides were prepared in good to excellent yields from enolizable ketones, whereas aldehydes afforded the corresponding gem-dihalides. The halogenation proceeded smoothly under mild conditions.