(1R)-1-(6-methylpyridin-3-yl)ethan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (1R)-1-(6-methylpyridin-3-yl)ethan-1-ol
• 英文别名: (1R)-1-(6-methylpyridin-3-yl)ethanol
• 化学式: C₈H₁₁NO
• 分子量: 137.181
• InChiKey: LYMOQGXOROSRPJ-SSDOTTSWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] 2,4-THIAZOLIDINEDIONE DERIVATIVES IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS<br/>[FR] DÉRIVÉS DE 2,4-THIAZOLIDINEDIONE DANS LE TRAITEMENT DE TROUBLES DU SYSTÈME NERVEUX CENTRAL
  申请人：MINORYX THERAPEUTICS S L

  公开号：WO2015150476A1

  公开（公告）日：2015-10-08

  The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy) benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.

  本发明提供了5-(4-(2-(5-(1-羟乙基)吡啶-2-基)乙氧基)苄基)噻唑二酮-2,4-二酮及其新的立体异构体，用于治疗中枢神经系统（NS）疾病。
• 2,4-THIAZOLIDINEDIONE DERIVATIVES IN THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS
  申请人：MINORYX THERAPEUTICS S.L.

  公开号：US20160235729A1

  公开（公告）日：2016-08-18

  The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy) benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.

  本发明提供了5-(4-(2-(5-(1-羟乙基)吡啶-2-基)乙氧基)苄基)噻唑烷-2,4-二酮及其新的立体异构体，用于治疗中枢神经系统（NS）疾病。
• 2,4-thiazolidinedione derivatives in the treatment of central nervous system disorders
  申请人：MINORYX THERAPEUTICS S.L.

  公开号：US10179126B2

  公开（公告）日：2019-01-15

  The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.

  本发明提供了用于治疗中枢神经系统（NS）疾病的 5-(4-(2-(5-(1-羟乙基)吡啶-2-基)乙氧基)苄基)噻唑烷-2,4-二酮和所述化合物的新型立体异构体。
• 2,4-Thiazolidinedione Derivatives in the Treatment of Central Nervous System Disorders
  申请人：Minoryx Therapeutics S.L.

  公开号：US20180133202A1

  公开（公告）日：2018-05-17

  The present invention provides 5-(4-(2-(5-(1-hydroxyethyl)pyridine-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione and novel stereoisomers of said compound for use in the treatment of central nervous system (NS) disorders.
• US9782395B2
  申请人：——

  公开号：US9782395B2

  公开（公告）日：2017-10-10