申请人:——
公开号:US20040151774A1
公开(公告)日:2004-08-05
Polymer foams and films for delivery of therapeutic agents to and through nasal, oral or vaginal mucosa and cornified or non-cornified epithelium of labia and scrotum. Polymer foams or absorbable or non-absorbable films containing a therapeutic agent incorporated therein wherein said agent is released from said foams or films upon placement of said foam or film on the surface epithelium of nasal, oral, or vaginal labia or scrotum. The foam or the film has a controllable rate of gelling, swelling and degradation and is preformed into a device or is applied as a coating to a surface of a more complex drug delivery system.
用于向鼻腔、口腔或阴道粘膜以及阴唇和阴囊的角化或非角化上皮输送治疗剂的聚合物泡沫和薄膜。聚合物泡沫或含有治疗剂的可吸收或不可吸收薄膜,其中所述治疗剂在所述泡沫或薄膜置于鼻腔、口腔或阴道阴唇或阴囊表面上皮时从所述泡沫或薄膜中释放出来。泡沫或薄膜的胶凝、膨胀和降解速度可控,可预制成装置,或作为涂层应用于更复杂的给药系统表面。