(3-Methylphenyl)methyl 6-aminohexanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (3-Methylphenyl)methyl 6-aminohexanoate
• 英文别名: (3-methylphenyl)methyl 6-aminohexanoate
• 化学式: C₁₄H₂₁NO₂
• 分子量: 235.32
• InChiKey: VDXSBZZXQARITE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  52.3
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Compositions and methods for modulating growth hormone receptor expression
  申请人：Ionis Pharmaceuticals, Inc.

  公开号：US11312964B2

  公开（公告）日：2022-04-26

  The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with excess growth hormone using antisense compounds or oligonucleotides targeted to growth hormone receptor (GHR).

  本发明的实施方案提供了利用针对生长激素受体（GHR）的反义化合物或寡核苷酸治疗、预防或改善与过量生长激素有关的疾病的方法、化合物和组合物。
• COMPOSITIONS AND METHODS FOR MODULATING GROWTH HORMONE RECEPTOR EXPRESSION
  申请人：Ionis Pharmaceuticals, Inc.

  公开号：US20210207146A1

  公开（公告）日：2021-07-08

  The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with excess growth hormone using antisense compounds or oligonucleotides targeted to growth hormone receptor (GHR).