hexahydrocannabinol | 946512-74-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: hexahydrocannabinol
• 英文别名: HHC；D4K2Zlp4DT；(6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
• CAS: 946512-74-9
• 化学式: C₂₁H₃₂O₂
• 分子量: 316.484
• InChiKey: XKRHRBJLCLXSGE-VNCLPFQGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N,O-双(三甲基硅烷基)三氟乙酰胺 、 hexahydrocannabinol 在 三甲基氯硅烷 作用下， 以 乙酸乙酯 为溶剂， 反应 0.5h， 生成
  参考文献：
  名称：

  Photochemistry of Cannabidiol (CBD) Revised. A Combined Preparative and Spectrometric Investigation

  摘要：

  DOI：

  10.1021/acs.jnatprod.1c00567
• 作为产物：
  描述：

  反式-薄荷基-2,8-二烯-1-醇 在 palladium 10% on activated carbon 、 对甲苯磺酸 作用下， 以 乙酸乙酯 、 甲苯 为溶剂， 120.0 ℃ 、101.33 kPa 条件下， 反应 8.0h， 生成 hexahydrocannabinol
  参考文献：
  名称：

  Photochemistry of Cannabidiol (CBD) Revised. A Combined Preparative and Spectrometric Investigation

  摘要：

  DOI：

  10.1021/acs.jnatprod.1c00567

文献信息

• Compositions and methods for reducing overdose
  申请人：Odidi Isa

  公开号：US10293046B2

  公开（公告）日：2019-05-21

  Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration of an addictive substance or any active substance and to prevent, reduce, inhibit, or delay purposeful or accidental overdose of an active substance by ingesting too many dosage forms at once, for example.

  提供给药制剂、其用途和制作方法是为了减少滥用、误用或不当使用成瘾物质或任何活性物质的可能性，并防止、减少、抑制或延缓因一次摄入过多剂型的活性物质而有目的或意外地过量使用。
• Studies Pertaining to the Emerging Cannabinoid Hexahydrocannabinol (HHC)
  作者：Daniel J. Nasrallah、Neil K. Garg

  DOI：10.1021/acschembio.3c00254

  日期：2023.9.15
• HYDROGENATION OF CANNABIS OIL
  申请人：Scialdone, Mark Andrew

  公开号：EP3291807B1

  公开（公告）日：2019-09-25
• Application System for a Plaster Containing an Active Ingredient and a Controlled-Release Agent for Said Active Ingredient
  申请人：Bartholomaus Johannes

  公开号：US20080274146A1

  公开（公告）日：2008-11-06

  The present invention relates to an application system for an active ingredient release system, comprising a film-form application strip, which is in each case bonded detachably to an active ingredient-containing plaster and a separate active ingredient release regulator separate there from.
• Abuse-Resistant Pharmaceutical Dosage Form
  申请人：Bartholomäus Johannes

  公开号：US20100221322A1

  公开（公告）日：2010-09-02

  A solid pharmaceutical dosage form that is safeguarded against abuse containing at least one active substance that could be subject to abuse and at least one antagonist for the active substance, which antagonist is spatially separate from the active substance. The active substance or substances is/are present in at least one subunit (a), and the at least one antagonist is present in at least one subunit (b), and the at least one antagonist in subunit (b) is to all intents and purposes not released in the body if the dosage form is correctly administered as prescribed.