N-(6-acetyl-1,3-benzodioxol-5-yl)-2-(3,5-dimethyl-1,2-oxazol-4-yl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: N-(6-acetyl-1,3-benzodioxol-5-yl)-2-(3,5-dimethyl-1,2-oxazol-4-yl)acetamide
• 化学式: C₁₆H₁₆N₂O₅
• 分子量: 316.31
• InChiKey: UUASKIGBVQSSTD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  90.7
• 氢给体数：
  1
• 氢受体数：
  6

文献信息

• [EN] ANTAGONISTS OF T2R54 AND COMPOSITIONS AND USES THEREOF<br/>[FR] ANTAGONISTES DE T2R54 ET COMPOSITIONS ET UTILISATIONS ASSOCIÉES
  申请人：FIRMENICH INCORPORATED

  公开号：WO2020033669A1

  公开（公告）日：2020-02-13

  The present disclosure generally provides compounds that antagonize certain T2R taste receptors, including related uses, methods, and compositions for the reduction of bitter taste and/or the enhancement of sweet taste. In certain aspects, the disclosure provides flavored articles or flavored compositions comprising such compounds, as well as uses of such compounds to reduce the bitter taste and/or enhance the sweet taste of such flavored articles or flavored compositions.