N-[2-(ethylamino)-2-oxoethyl]-4-nitrobenzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[2-(ethylamino)-2-oxoethyl]-4-nitrobenzamide
• 化学式: C11H13N3O4
• 分子量: 251.24
• InChiKey: CDFJGBYPKZBOJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  104
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• US7902330B2
  申请人：——

  公开号：US7902330B2

  公开（公告）日：2011-03-08
• [EN] PROTEIN KINASE INHIBITORS AND METHODS FOR IDENTIFYING SAME<br/>[FR] INHIBITEURS DE PROTEINES KINASES ET LEURS METHODES D'IDENTIFICATION
  申请人：EINSTEIN COLL MED

  公开号：WO2005079300A2

  公开（公告）日：2005-09-01

  Inhibitors of protein kinase C (PKC)alpha, PKCdelta and PKCzeta are provided which are selective for those PKC isotypes. Combinatorial libraries for identifying protein kinases are also provided, as are methods of identifying protein kinases using those libraries. Additionally, methods of treating a mammal having a deleterious condition, where the condition is dependent on a protein kinase for induction or severity, are provided. Methods of inhibiting protein kinases are also provided.