对乙氧卡因 | 136-46-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 对乙氧卡因
• 中文别名: 盐酸对乙氧卡因
• 英文名称: Diethoxin
• 英文别名: 4-ethoxy-benzoic acid-(2-diethylamino-ethyl ester); hydrochloride；4-Aethoxy-benzoesaeure-(2-diaethylamino-aethylester); Hydrochlorid；2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride；Intracain (R)；2-(diethylamino)ethyl 4-ethoxybenzoate;hydron;chloride
• CAS: 136-46-9
• 化学式: C₁₅H₂₃NO₃*ClH
• 分子量: 301.813
• InChiKey: SFLZPZAKIKUJKP-UHFFFAOYSA-N

物化性质

• 熔点：
  172.5-173.5°

计算性质

• 辛醇/水分配系数(LogP)：
  3.01
• 重原子数：
  20
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  38.8
• 氢给体数：
  1
• 氢受体数：
  4

安全信息

• 海关编码：
  2922509090

反应信息

• 作为产物：
  描述：

  4-乙氧基苯甲酰氯 、 二乙氨基乙醇 生成 对乙氧卡因
  参考文献：
  名称：

  Eckert; Wachtel, Arzneimittel-Forschung/Drug Research, 1983, vol. 33, # 1, p. 98 - 100

  摘要：

  DOI：

文献信息

• Topical analgesic
  申请人：Concept Matrix Solutions

  公开号：US11116780B2

  公开（公告）日：2021-09-14

  Provided herein is a topical analgesic composition that includes an external analgesic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical analgesic composition.

  本文提供了一种局部镇痛组合物，它包括一种外用镇痛剂、一种或多种药学上可接受的赋形剂以及大麻素、萜烯和类黄酮中的至少一种。还提供了一种方法，包括向受试者（例如人类）的皮肤表面局部施用该局部镇痛组合物。
• PAIN-RELIEVING TOPICAL COMPOSITIONS
  申请人：INNOCAN PHARMA LTD.

  公开号：EP3735225A1

  公开（公告）日：2020-11-11
• Compositions and Methods for Removing Urushiol and Treating the Resulting Skin Condition
  申请人：Hare D. William

  公开号：US20080107742A1

  公开（公告）日：2008-05-08

  The present application is directed to various compositions to treat the itching and conditions that result from contracting poison ivy, poison oak, and poison sumac, as well as other plant and substances that contain substances that lead to a skin reaction but that upon removal alleviate the symptoms of the condition. In particular, the compositions described herein are useful for removing urushiol after it has contacted the skin. The compositions include granules or other scrubbing means to reach the urushiol in the skin, a mixture of surfactants to form a complex with the urushiol, counter-irritants to provide a soothing sensation to the irritated skin, and other functional ingredients to provide additional benefits to the individual who has contacted urushiol.
• SYSTEMS AND METHODS FOR COLLECTING, TRANSPORTING AND REPURPOSING OR DESTROYING UNUSED PHARMACEUTICALS
  申请人：Sharps Compliance, Inc.

  公开号：US20150152348A1

  公开（公告）日：2015-06-04

  Systems and methods implementing the systems including a facility including a plurality of collection apparatuses distributed in the facility for ease of collection and transportation. The system also includes transportation subsystems for shipping filled inner containers to a processing subsystem and for transporting a fuel material or a land fillable material to incineration or landfill subsystems. The systems may also include a monitoring subsystem for monitoring the deployed collection apparatuses, inner containers, the fuel material and the land fillable material.
• TOPICAL ANALGESIC
  申请人：Concept Matrix Solutions

  公开号：US20210015836A1

  公开（公告）日：2021-01-21

  Provided herein is a topical analgesic composition that includes an external analgesic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical analgesic composition.