benzyl 2-(acetoxymethyl)-3-hydroxy-2-methylpropanoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzyl 2-(acetoxymethyl)-3-hydroxy-2-methylpropanoate
• 英文别名: Benzyl 2-(acetoxymethyl)-3-hydroxy-2-methylpropanoate；benzyl 2-(acetyloxymethyl)-3-hydroxy-2-methylpropanoate
• 化学式: C₁₄H₁₈O₅
• 分子量: 266.294
• InChiKey: OYTGLDKWNHAGAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  19
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  72.8
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  苄基3-羟基-2-(羟基甲基)-2-甲基丙酸酯 在 4-二甲氨基吡啶 作用下， 以 二氯甲烷 、 异丙醚 、 正丁醇 为溶剂， 反应 20.0h， 生成 benzyl 2-(acetoxymethyl)-3-hydroxy-2-methylpropanoate
  参考文献：
  名称：

  Highly Selective Biocatalytic Transesterification Reactions on Aryl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoates

  摘要：

  DOI：

  10.1007/s10562-014-1447-6

文献信息

• ANTIMICROBIAL CATIONIC POLYAMINES
  申请人：International Business Machines Corporation

  公开号：US20150342984A1

  公开（公告）日：2015-12-03

  Antimicrobial, non-hemolytic cationic polyamines were prepared by treating partially N-acylated polyethylenimines and/or partially oxidized polyethylenimines with a protic acid. The cationic polyamines can have a linear or branched polyethylenimine backbone structure. Preferably, the cationic polyamines comprise pendant urea groups, which can be introduced via a cyclic carbonate comprising a pendant urea group. The cationic polyamines can be active against a tuberculosis mycobacterium at low concentration. The cationic polyamines are also effective against Gram-negative Escherichia coli and Pseudomonas aeruginosa , Gram-positive Staphylococcus aureus , and fungus Candida albicans in solution and in the form of a film.

  抗菌、非溶血性阳离子聚胺是通过用一种质子酸处理部分N-酰化聚乙烯亚胺和/或部分氧化聚乙烯亚胺制备的。这些阳离子聚胺可以具有线性或支链聚乙烯亚胺骨架结构。最好的情况是，这些阳离子聚胺包括吊挂脲基团，可以通过含有吊挂脲基团的环状碳酸酯引入。这些阳离子聚胺在低浓度下可以对结核分枝杆菌起作用。这些阳离子聚胺对革兰氏阴性大肠杆菌和铜绿假单胞菌、革兰氏阳性金黄色葡萄球菌以及真菌白色念珠菌在溶液中和膜的形式中也具有有效性。
• BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS
  申请人：Cheng Wei

  公开号：US20140080215A1

  公开（公告）日：2014-03-20

  A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n′+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L′ is a divalent radical comprising 3 to 30 carbons, and q/(n′+q)×100% equals about 9% to about 47%.
• US9399044B2
  申请人：——

  公开号：US9399044B2

  公开（公告）日：2016-07-26
• [EN] LOW MOLECULAR WEIGHT BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS<br/>[FR] POLYAMINES RAMIFIÉES À FAIBLE POIDS MOLÉCULAIRE POUR L'ADMINISTRATION DE MATIÈRES BIOLOGIQUEMENT ACTIVES
  申请人：IBM

  公开号：WO2014042922A1

  公开（公告）日：2014-03-20

  A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n' greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2); wherein (n'+q) is a number equal to about 8 to about 12, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L' is a divalent linking group comprising 3 to 30 carbons, and q/(n' + q) x 100% equals about 9% to about 40%.
• [EN] BRANCHED POLYAMINES FOR DELIVERY OF BIOLOGICALLY ACTIVE MATERIALS<br/>[FR] POLYAMINES RAMIFIÉES POUR L'ADMINISTRATION DE MATIÈRES BIOLOGIQUEMENT
  申请人：IBM

  公开号：WO2014042920A1

  公开（公告）日：2014-03-20

  A branched polyamine comprises about 45 to about 70 backbone tertiary amine groups, about 90 to about 140 backbone secondary amine groups, a positive number n' greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): — CH2-CH2-N— Is. ^O-L'-O H (2), wherein (n'+q) is a number equal to about 45 to about 70, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L' is a divalent radical comprising 3 to 30 carbons, and q/(n' + q) x 100% equals about 9% to about 47%.