N-(3-chloro-2-methylphenyl)-3-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]benzamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3-chloro-2-methylphenyl)-3-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]benzamide
• 化学式: C₂₀H₁₉ClN₂O₃
• mdl: MFCD09474482
• 分子量: 370.8
• InChiKey: VJWISMHHWXXRBV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  64.4
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Compounds for Treating Rac-GTPase Mediated Disorder
  申请人：Children's Medical Center Corporation

  公开号：US20150265608A1

  公开（公告）日：2015-09-24

  This disclosure relates to compositions including certain compounds identified by a quantitative, high throughput assay to be effective in the treatment of chronic myelogenous leukemia, as well as methods for the manufacture of and the use of these compounds for treating a Rac-GTPase mediated disorder.