对甲基苯甲醇烟酸酯 | 56614-95-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 对甲基苯甲醇烟酸酯
• 英文名称: nicotinic acid 1-(4-methaneylphenyl)ethyl ester
• 英文别名: nicotinic acid 1-(4-methylphenyl)ethyl ester；1-(4-methylphenyl)ethyl nicotinate；3-Pyridinecarboxylic acid, 1-(4-methylphenyl)ethyl ester；1-(4-methylphenyl)ethyl pyridine-3-carboxylate
• CAS: 56614-95-0
• 化学式: C₁₅H₁₅NO₂
• 分子量: 241.29
• InChiKey: VUICSPKQAQGLBU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• ANTI-AGING AGENT CONTAINING ARCTIGENIN DERIVATIVE
  申请人：ROHTO Pharmaceutical Co., Ltd.

  公开号：US20150093345A1

  公开（公告）日：2015-04-02

  An arctigenin derivative used for anti-aging treatment, including protection of the skin from the sun and recovery of skin elasticity. A variety of fatty acid ester derivatives, alcohol ether derivatives and alkylated derivatives are used as the arctigenin derivatives. Agents for controlling ET-1 production, elastase inhibitors, and anti-inflammatory agents are prepared. Such arctigenin derivatives are particularly useful as an external agent for the skin, such as an anti-inflammatory external agent, a sunscreen external agent, or an external agent for recovering elasticity.

  一种用于抗衰老治疗的牛蒡素衍生物，包括保护皮肤免受阳光伤害和恢复皮肤弹性。使用各种脂肪酸酯衍生物、醇醚衍生物和烷基衍生物作为牛蒡素衍生物。制备用于控制ET-1产生的药剂、弹性蛋白酶抑制剂和抗炎药剂。这种牛蒡素衍生物特别适用于皮肤外用剂，如抗炎外用剂、防晒外用剂或恢复弹性的外用剂。
• COSMETIC COMPOSITION
  申请人：Rohto Pharmaceutical Co., Ltd.

  公开号：EP3616683A1

  公开（公告）日：2020-03-04

  Provided is a cosmetic composition that maintains high stability and restrains from becoming cloud. This cosmetic composition is prepared by including (A) polyoxyethylene polyoxypropylene glycol, and (B) an amino acid based surfactant having, in a single molecule thereof, two or more hydrophobic groups and two or more hydrophilic groups. Furthermore, provided is a method of giving a cloudiness-restraining effect to a cosmetic composition, including causing the component (A) and the component (B) to coexist with each other in the cosmetic composition.

  本发明提供了一种化妆品组合物，它能保持高稳定性并防止变浊。 这种化妆品组合物的制备方法是：(A) 聚氧乙烯聚氧丙烯二醇；(B) 氨基酸基表面活性剂，在其单个分子中具有两个或两个以上的疏水基团和两个或两个以上的亲水基团。此外，还提供了一种使化妆品组合物具有抑浊效果的方法，包括使组分（A）和组分（B）在化妆品组合物中共存。
• SOLID OILY EXTERNAL COMPOSITION
  申请人：ROHTO PHARMACEUTICAL CO., LTD.

  公开号：US20210038616A1

  公开（公告）日：2021-02-11

  A solid oily external composition including at least one selected from the group consisting of (A) a steroid compound and an antihistamine is smoothly applicable onto a skin or a mucous membrane. The composition can be a stick-shaped solid composition. The content of the steroid compound (A) can be 0.0001 to 5% by weight relative to the total amount of the composition, and the content of the antihistamine (B) can be 0.01 to 5% by weight relative to the total amount of the composition.
• US9675538B2
  申请人：——

  公开号：US9675538B2

  公开（公告）日：2017-06-13