(2,3,4,5,6-五氯苯基)丁酸酯 | 7476-90-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 中文名称: (2,3,4,5,6-五氯苯基)丁酸酯
• 英文名称: Pentachlorphenyl-n-butyrat
• 英文别名: butyric acid pentachlorophenyl ester；Buttersaeure-pentachlorphenylester；2.3.4.5.6-Pentachlor-1-butyryloxy-benzol；(Pentachlor-phenyl)-butyrat；Pentachlorophenyl butyrate；(2,3,4,5,6-pentachlorophenyl) butanoate
• CAS: 7476-90-6
• 化学式: C₁₀H₇Cl₅O₂
• 分子量: 336.429
• InChiKey: KCXVYDVAQYFMHH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  五氯酚 、 丁酰氯 在 吡啶 作用下， 生成 (2,3,4,5,6-五氯苯基)丁酸酯
  参考文献：
  名称：

  Ssuworow et al., Zhurnal Obshchei Khimii, 1957, vol. 27, p. 1945,1956

  摘要：

  DOI：

文献信息

• Process for production of chlorinated sucrose based on hydrophobic affinity chromatography
  申请人：Ratnam Rakesh

  公开号：US20100222570A1

  公开（公告）日：2010-09-02

  This invention relates to a process for selective capture, isolation and purification of chlorinated sucrose compounds, including chlorinated sucrose, their precursors and derivatives, including trichlorogalactosucrose (TGS), directly from chlorinated reaction mixture by column chromatography on adsorbents and under conditions which result in specific and selective affinity towards one or more of chlorinated sucrose compound. The process also integrates de-esterification of chlorinated sucrose esters adsorbed on the adsorbent while they are being treated with desorbent. The process also provides a novel approach to concentration and crystallization of TGS. The chlorinated sucrose derivatives, including TGS, thus isolated are substantially free from most impurities, salts and organic solvents. The process has high recovery of more than 95% in terms of desired chlorinated sucrose derivatives including TGS.

  本发明涉及一种从氯化反应混合物中通过吸附剂柱层析和在特定条件下对氯化蔗糖化合物，包括氯化蔗糖、其前体和衍生物，如三氯半乳糖蔗糖（TGS）进行选择性捕获、分离和纯化的过程。该过程还结合了在吸附剂上吸附的氯化蔗糖酯在处理解吸剂时的去酯化。该过程还提供了一种新的浓缩和结晶TGS的方法。因此，分离出的包括TGS在内的氯化蔗糖衍生物基本上不含大多数杂质、盐和有机溶剂。该过程具有高达95%以上的期望氯化蔗糖衍生物，包括TGS的高回收率。
• Barral, Bulletin de la Societe Chimique de France, 1895, vol. <3> 13, p. 340,343
  作者：Barral

  DOI：——

  日期：——
• Byrde; Woodcock, Annals of Applied Biology, 1956, vol. 44, p. 138,139
  作者：Byrde、Woodcock

  DOI：——

  日期：——
• PROCESS FOR PRODUCTION OF CHLORINATED SUCROSE BASED ON HYDROPHOBIC AFFINITY CHROMATOGRAPHY.
  申请人：Pharmed Medicare Private Limited

  公开号：EP1928891A2

  公开（公告）日：2008-06-11
• EP1928891A4
  申请人：——

  公开号：EP1928891A4

  公开（公告）日：2009-06-17