disodium;4-[(2Z)-2-(5-carbamoyl-1-ethyl-4-methyl-2,6-dioxopyridin-3-ylidene)hydrazinyl]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulfonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: disodium;4-[(2Z)-2-(5-carbamoyl-1-ethyl-4-methyl-2,6-dioxopyridin-3-ylidene)hydrazinyl]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulfonate
• 化学式: C18H14Cl2N8Na2O9S2
• 分子量: 667.4
• InChiKey: JUNRGNKPIKIXLL-BGBYJAETSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -6.3
• 重原子数：
  41
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  287
• 氢给体数：
  3
• 氢受体数：
  15

文献信息

• Methods for tailoring the refractive index of lenses
  申请人：Battelle Memorial Institute

  公开号：US10254562B2

  公开（公告）日：2019-04-09

  Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

  本发明公开了改变透镜（如眼内透镜）功率的方法和装置。在一种方法中，镜片由含有可交联悬垂基团的单一聚合物基质组成，其中聚合物基质在交联时体积增大。镜片不含游离单体。在暴露于紫外线辐射时，交联会使镜片的暴露部分体积增大，从而导致折射率增加。在另一种方法中，镜片由含有光漂白发色团的聚合物基质组成。暴露在紫外线辐射下时，光漂白会导致暴露部分的折射率降低，而镜片厚度不会发生任何变化。这些方法避免了等待扩散发生以改变镜片形状的需要，也避免了第二次暴露于辐射以锁定镜片变化的需要。
• Ionically modified silicones, compositions, and medical devices formed therefrom
  申请人：Momentive Performance Materials Inc.

  公开号：US11254789B2

  公开（公告）日：2022-02-22

  A hydrophilic silicone, compositions comprising the same, and articles comprising the same are shown and described herein. The hydrophilic silicone is an ionically modified silicone compound wherein the compound has a net neutral charge. The hydrophilic silicone compounds may be provided as part of a composition, e.g., a composition suitable for forming a hydrogel, which may be employed to form a film material and even an article (e.g., in a contact lens).

  本文展示并描述了一种亲水性硅氧烷、包含亲水性硅氧烷的组合物以及包含亲水性硅氧烷的物品。亲水性硅氧烷是一种离子改性硅氧烷化合物，其中的化合物具有净中性电荷。亲水性有机硅化合物可作为组合物的一部分提供，例如，适合形成水凝胶的组合物，该组合物可用于形成薄膜材料，甚至物品（例如，隐形眼镜）。
• ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND
  申请人：Performance Indicator, LLC

  公开号：EP3174953A1

  公开（公告）日：2017-06-07
• ENVIRONMENTALLY RESPONSIVE CHROMATIC LUMINESCENT COMPOSITIONS WITH IMPROVED HAND
  申请人：Bambu Vault LLC

  公开号：EP3174953B1

  公开（公告）日：2020-09-02
• EP3583176B1
  申请人：——

  公开号：EP3583176B1

  公开（公告）日：2020-12-16