(4Z)-2,5-dimethyl-1-(2-phenylethyl)piperidin-4-one oxime

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4Z)-2,5-dimethyl-1-(2-phenylethyl)piperidin-4-one oxime
• 英文别名: (NZ)-N-[2,5-dimethyl-1-(2-phenylethyl)piperidin-4-ylidene]hydroxylamine
• 化学式: C₁₅H₂₂N₂O
• 分子量: 246.35
• InChiKey: RSOJDXFITJOAFZ-NXVVXOECSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  35.8
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• OPIOID ANTAGONIST COMPOUNDS AND METHODS OF TREATING MEDICAL CONDITIONS
  申请人：VDM Biochemicals, Inc.

  公开号：US20220105081A1

  公开（公告）日：2022-04-07

  The present invention is aimed at providing an opioid antagonist compound and its medical uses. The medical uses the compound of formula (I) (shown below) include complete or partial reversal of narcotic depression with minimal to no withdrawal symptoms, treatment of opioid addiction, depression, opioid withdrawal side effect treatment, schizophrenia, hypertension, scleroderma, dyskinesia, bipolar disorder, ADHD, addictive behaviors, Parkinson's disease, eating disorders, anorexia nervosa, migraine, and memory disorders.
• US9650338B1
  申请人：——

  公开号：US9650338B1

  公开（公告）日：2017-05-16