(5,6,7,8-四氢-2-萘己烯甲基)胺 | 15402-69-4

• 物质功能分类: 生物 - 细胞培养 - 培养基
• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 中文名称: (5,6,7,8-四氢-2-萘己烯甲基)胺
• 英文名称: C-(5,6,7,8-tetrahydro-[2]naphthyl)-methylamine
• 英文别名: C-(5,6,7,8-Tetrahydro-[2]naphthyl)-methylamin；2-Aminomethyl-5.6.7.8-tetrahydro-naphthalin；(Tetralyl-(6)-methyl)-amin；6-Aminomethyl-tetralin；(5,6,7,8-Tetrahydro-2-naphthalenylmethyl)amine；5,6,7,8-tetrahydronaphthalen-2-ylmethanamine
• CAS: 15402-69-4
• 化学式: C₁₁H₁₅N
• 分子量: 161.247
• InChiKey: SGCPAUPWLDLCBN-UHFFFAOYSA-N

物化性质

• 沸点：
  284.2±9.0 °C(Predicted)
• 密度：
  1.031±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

安全信息

• 海关编码：
  2921499090

反应信息

• 作为产物：
  描述：

  6-氰基-1,2,3,4-四氢萘 在 乙醇 、 sodium 作用下， 生成 (5,6,7,8-四氢-2-萘己烯甲基)胺
  参考文献：
  名称：

  v. Braun, Chemische Berichte, 1922, vol. 55, p. 1708

  摘要：

  DOI：

文献信息

• [EN] GUANIDINE COMPOUNDS AND USE THEREOF<br/>[FR] COMPOSÉS DE GUANIDINE ET LEUR UTILISATION
  申请人：HANALL BIOPHARMA CO LTD

  公开号：WO2015160220A1

  公开（公告）日：2015-10-22

  The present invention relates to guanidine compounds for inhibiting mitochondrial oxidative phosphorylation (OXPHOS) and use thereof. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating a OXPHOS-related disease, particularly cancer by inhibiting mitochondrial oxidative phosphorylation and reprogramming cellular metabolism.

  本发明涉及用于抑制线粒体氧化磷酸化（OXPHOS）的胍啉化合物及其使用。更具体地，本发明涉及一种用于预防或治疗与OXPHOS相关的疾病，特别是通过抑制线粒体氧化磷酸化和重编程细胞代谢的药物组合物。
• Pesticidial Condensed-Ring Aryl Compounds
  申请人：Murata Tetsuya

  公开号：US20110071141A1

  公开（公告）日：2011-03-24

  Condensed-ring aryl compounds of formula (I) and use of the same as a agrochemical for controlling noxious organisms wherein (X) m Q, A, R 1 , (Y) n and the grouping —W 1 —W 2 —W 3 —W 4 — are as defined herein.

  公式（I）的紧缩环芳基化合物和将其用作农药，用于控制有害生物，其中（X）mQ，A，R1，（Y）n和基团—W1—W2—W3—W4—如本文所定义。
• ATTRACTANT AND FEEDING STIMULANT FOR COCKROACH
  申请人：TAISHO PHARMACEUTICAL CO. LTD

  公开号：EP0638237A1

  公开（公告）日：1995-02-15

  An attractant and feeding stimulant for cockroach containing at least one compound represented by general formula (I) wherein R represents amino or aminomethyl. It has a significantly potent attractant and feeding stimulating action on male and female cockroaches of the types known as the domestic pest.

  一种蟑螂引诱剂和摄食刺激剂，含有至少一种由通式（I）代表的化合物，其中 R 代表氨基或氨基甲基。它对雌雄蟑螂具有明显的引诱和摄食刺激作用，这些蟑螂被称为家养害虫。
• Cloning and Characterization of the Promoter Region of the Human CD83 Gene
  作者：S BERCHTOLD

  DOI：10.1078/0171-2985-00128

  日期：——

  Human CD83 (hCD83) is a glycoprotein expressed predominantly on the surface of dendritic cells (DC). To get insight into the regulation of hCD83 expression, we cloned a 3037 by fragment upstream of the translation initiation codon. Deletion mutants were constructed revealing highest promoter activity in the -261 fragment containing four SP1 binding sites and one NF-kappaB element. Electrophoretic mobility shift assays demonstrated the specific interaction of NF-kappaB factors with the NF-kappaB element as well as specific binding of SP1 and SP3 to the SP1 binding site. The hCD83 promoter was inducible by TNF-alpha. This inducibility was strictly dependent on the intact NF-kappaB element.
• ATTRACTING AND INGESTION-STIMULATING AGENT FOR COCKROACH
  申请人：TAISHO PHARMACEUTICAL CO. LTD

  公开号：EP0598122A1

  公开（公告）日：1994-05-25