2-(3-Fluorophenyl)-7-azabicyclo[2.2.1]heptane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: 2-(3-Fluorophenyl)-7-azabicyclo[2.2.1]heptane
• 化学式: C₁₂H₁₄FN
• 分子量: 191.24
• InChiKey: JUIMILKYDTXZIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Compounds and methods for promoting smoking cessation
  申请人：Research Triangle Institute

  公开号：EP2494975A1

  公开（公告）日：2012-09-05

  Compounds and methods for promoting smoking cessation. The compounds may be used to treat a variety of other conditions and disease states.

  促进戒烟的化合物和方法。这些化合物可用于治疗各种其他病症和疾病状态。
• NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS IN THE TREATMENT OF RESTLESS LEGS SYNDROME
  申请人：Pfizer Products Inc.

  公开号：EP1439836A1

  公开（公告）日：2004-07-28
• [EN] NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS IN THE TREATMENT OF RESTLESS LEGS SYNDROME<br/>[FR] AGONISTES DU RECEPTEUR D'ACETYLCHOLINE NICOTINIQUE POUR TRAITER LES IMPATIENCES DES MEMBRES INFERIEURS
  申请人：PFIZER PROD INC

  公开号：WO2003037329A1

  公开（公告）日：2003-05-08

  This invention relates to the use of nicotinic acetylcholine receptor agonists for the treatment of restless legs syndrome (RLS). The invention further relates to the use of a nicotinic acetylcholine receptor agonist in the manufacture of a medicament for the treatment of RLS. The present invention also relates to a pharmaceutical composition for the treatment of RLS containing a nicotinic actylcholine receptor agonist.