(4,4-Dimethyl-2-oxooxolan-3-yl) (4-methoxyphenyl)methyl carbonate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4,4-Dimethyl-2-oxooxolan-3-yl) (4-methoxyphenyl)methyl carbonate
• 化学式: C₁₅H₁₈O₆
• 分子量: 294.3
• InChiKey: GKWZVHKEJLRXFK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  21
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  71.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• US6469193B1
  申请人：——

  公开号：US6469193B1

  公开（公告）日：2002-10-22
• [EN] EFFICIENT SYNTHESIS OF ALKYL CARBONATES<br/>[FR] SYNTHESE EFFICACE DE CARBONATES D'ALKYLES
  申请人：UNIV SOUTH FLORIDA

  公开号：WO2000050376A2

  公开（公告）日：2000-08-31

  Efficient synthetic methods towards mixed aliphatic carbonates through the three component couplings of aliphatic alcohols, alkyl halides and carbon dioxide in the presence of cesium carbonate and tetrabutylammonium iode (TBAI). Due to their enhanced nucleophilicities, cesium alkoxides are smoothly incorporated into CO2, allowing for mild reaction conditions such as ambient temperatures and short reaction durations. Various primary and secondary substrates are compatible under the standard conditions, offering high yields, while chiral templates such as α-hydroxy carbonyls are resistant to racemization.