4,5-Didodecyl-1,3-oxazolidin-2-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 4,5-Didodecyl-1,3-oxazolidin-2-one
• 化学式: C₂₇H₅₃NO₂
• 分子量: 423.7
• InChiKey: YJTIEUSRCIXIPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.1
• 重原子数：
  30
• 可旋转键数：
  22
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Oxazolidinones pour une utilisation cosmétique cutanée
  申请人：Laboratoires Expanscience

  公开号：EP2266530A1

  公开（公告）日：2010-12-29

  L'invention a également pour objet une méthode de traitement cosmétique des peaux et/ou des muqueuses sensibles, irritées, intolérantes, à tendance allergique, âgées, présentant un trouble de la barrière cutanée, ou présentant un déséquilibre immunologique non pathologique, consistant à appliquer sur la peau et/ou les muqueuses une composition, comprenant au moins une oxazolidinone.

  本发明还涉及一种对敏感、易激惹、不耐受、易过敏或老年皮肤和/或粘膜，或皮肤屏障失调的皮肤，或非病理性免疫失衡的皮肤进行美容治疗的方法，包括在皮肤和/或粘膜上涂抹包含至少一种噁唑烷酮的组合物。
• Composition comprising at least one oxazolin for inhibiting langerhans cell migratio, and uses thereof
  申请人：Msika Philippe

  公开号：US20050075380A1

  公开（公告）日：2005-04-07

  The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor a PKC inhibitor, an anti-inflamatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.

  本发明涉及一种至少含有恶唑啉的组合物，该组合物可选择性地与至少一种化合物结合使用，如金属蛋白酶抑制剂、PKC 抑制剂、抗炎剂、舒缓剂、免疫抑制剂、离子螯合剂、烷醇酰胺、恶唑烷酮和氨基甲酸衍生物。本发明还涉及将这种组合物用作药物，特别是用于预防或治疗过敏性和/或炎症性和/或刺激性皮肤病或由危险信号引起的皮肤病。本发明还涉及一种对敏感、刺激、不耐受、易过敏、老化的皮肤和/或表现出皮肤屏障失调或表现出非病理性免疫失衡的粘膜进行美容治疗的方法，该方法包括在皮肤和/或粘膜上涂抹这种组合物。
• Composition comprising at least one alkanolamide for inhibiting langerhans cells migration, and uses thereof
  申请人：Msika Philipe

  公开号：US20050075397A1

  公开（公告）日：2005-04-07

  The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.

  本发明涉及一种至少含有一种烷醇酰胺的组合物，该组合物可与至少一种化合物如金属蛋白酶抑制剂、PKC 抑制剂、消炎剂、舒缓剂、免疫抑制剂、离子螯合剂、噁唑啉、噁唑烷酮和氨基甲酸衍生物结合使用。本发明还涉及将此类组合物用作药物，特别是用于预防或治疗过敏性和/或炎症性和/或刺激性皮肤病或由危险信号引起的皮肤病。本发明还涉及一种对敏感、刺激、不耐受、易过敏、老化的皮肤和/或表现出皮肤屏障失调或表现出非病理性免疫失衡的粘膜进行美容治疗的方法，该方法包括在皮肤和/或粘膜上涂抹这种组合物。
• Composition comprising at least one alkanolamide to inhibit megration of langerhans cells and uses therof
  申请人：Msika Philippe

  公开号：US20060194881A1

  公开（公告）日：2006-08-31

  The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.

  本发明涉及一种至少含有一种烷醇酰胺的组合物，该组合物可与至少一种化合物如金属蛋白酶抑制剂、PKC 抑制剂、消炎剂、舒缓剂、免疫抑制剂、离子螯合剂、噁唑啉、噁唑烷酮和氨基甲酸衍生物结合使用。本发明还涉及将此类组合物用作药物，特别是用于预防或治疗过敏性和/或炎症性和/或刺激性皮肤病或由危险信号引起的皮肤病。本发明还涉及一种对敏感、刺激、不耐受、易过敏、老化的皮肤和/或表现出皮肤屏障失调或表现出非病理性免疫失衡的粘膜进行美容治疗的方法，该方法包括在皮肤和/或粘膜上涂抹这种组合物。
• COMPOSITION COMPRENANT AU MOINS UN ALCANOLAMIDE POUR INHIBER LA MIGRATION DES CELLULES DE LANGERHANS ET SES UTILISATIONS
  申请人：Laboratoires Expanscience

  公开号：EP1458347B1

  公开（公告）日：2016-09-28