(E)-1,2-双(4-(氯甲基)苯基)乙烯 | 1012036-95-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: (E)-1,2-双(4-(氯甲基)苯基)乙烯
• 英文名称: (E)-1,2-bis(4-(chloromethyl)phenyl)ethene
• 英文别名: 1-(chloromethyl)-4-[(E)-2-[4-(chloromethyl)phenyl]ethenyl]benzene
• CAS: 1012036-95-1
• 化学式: C₁₆H₁₄Cl₂
• 分子量: 277.193
• InChiKey: QEQPKDTXCBNFHR-OWOJBTEDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  (E)-1,2-双(4-(氯甲基)苯基)乙烯 、 4-乙烯基苯甲酸 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 4-二甲氨基吡啶 、 Wang resin 、 N,N'-二异丙基碳二亚胺 、 三氟乙酸 作用下， 以 N,N-二甲基甲酰胺 、 二氯甲烷 为溶剂， 反应 21.0h， 生成
  参考文献：
  名称：

  固相支持的交叉易位和非固定化烯烃的均聚化作用

  摘要：

  在第二代Grubbs和Hoveyda-Grubbs预催化剂的存在下，我们使用不同的烯烃伙伴制备了固定化烯烃作为交叉复分解的模型。我们已经证明固相交叉复分解强烈地依赖于未固定化烯烃的均二聚化程度和这种均二聚体的反应性。与在均相中一样，Hoveyda-Grubbs预催化剂对于固定化的α，β-不饱和羰基化合物更好。

  DOI：

  10.1021/jo7025433
• 作为产物：
  描述：

  4-氯甲基苯乙烯 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 以 二氯甲烷 为溶剂， 反应 20.0h， 生成 (E)-1,2-双(4-(氯甲基)苯基)乙烯
  参考文献：
  名称：

  固相支持的交叉易位和非固定化烯烃的均聚化作用

  摘要：

  在第二代Grubbs和Hoveyda-Grubbs预催化剂的存在下，我们使用不同的烯烃伙伴制备了固定化烯烃作为交叉复分解的模型。我们已经证明固相交叉复分解强烈地依赖于未固定化烯烃的均二聚化程度和这种均二聚体的反应性。与在均相中一样，Hoveyda-Grubbs预催化剂对于固定化的α，β-不饱和羰基化合物更好。

  DOI：

  10.1021/jo7025433

文献信息

• Merging Grubbs second-generation catalyst with photocatalysis enables<i>Z</i>-selective metathesis of olefins: scope, limitations, and mechanism
  作者：Saïf Eddine Chérif、Avisek Ghosh、Saloua Chelli、Isabelle M. Dixon、Jamil Kraiem、Sami Lakhdar

  DOI：10.1039/d2sc03961c

  日期：——

  Olefin cross-metathesis is a cornerstone reaction in organic synthesis where stereoselectivity is typically governed by the structure of the catalyst. In this work, we show that merging Grubbs second generation catalyst, a classical E-selective catalyst, with a readily available photocatalyst, enables the exclusive formation of the contra-thermodynamic Z-isomer. The scope and limitations of this unprecedented

  烯烃交叉复分解是有机合成中的基石反应，其中立体选择性通常由催化剂的结构决定。在这项工作中，我们展示了将 Grubbs 第二代催化剂（一种经典的E选择性催化剂）与现成的光催化剂合并，能够独家形成反热力学Z异构体。基于计算和实验机制数据讨论了这种前所未有的方法的范围和局限性。
• Modification of the Optoelectronic Properties of Membranes via Insertion of Amphiphilic Phenylenevinylene Oligoelectrolytes
  作者：Logan E. Garner、Juhyun Park、Scott M. Dyar、Arkadiusz Chworos、James J. Sumner、Guillermo C. Bazan

  DOI：10.1021/ja1016156

  日期：2010.7.28

  We report on the modification of membranes by incorporation of phenylenevinylene oligoelectrolytes with the goal of tailoring their optical and electronic properties and their applications. A water-soluble distyrylstilbene oligoelectrolyte (DSSN+), capped at each end with nitrogen bound, terminally charged pendant groups, was synthesized. The photophysical and solvatochromatic properties of DSSN+ and the shorter distyrylbenzene analogue DSBN+ were probed and found to be useful for characterizing insertion into membranes based on phospholipid vesicle systems. A combination of UV/visible absorbance and photoluminescence spectroscopies, together with confocal microscopy, were employed to confirm membrane incorporation. Examination of the emission intensity profile in stationary multilamellar vesicles obtained with a polarized excitation source provides insight into the orientation of these chromophores within lipid bilayers and indicates that these molecules are highly ordered, such that the hydrophobic electronically delocalized region positions within the inner membrane with the long molecular axis perpendicular to the bilayer plane. Cyclic voltammetry experiments provide evidence that DSSN+ and DSBN+ facilitate transmembrane electron transport across lipid bilayers supported on glassy carbon electrodes. Additionally, the interaction with living microorganisms was probed. Fluorescence imaging indicates that DSSN+ and DSBN+ preferentially accumulate within cell membranes. Furthermore, notable increases in yeast microbial fuel cell performance were observed when employing DSSN+ as the electron transport mediator.
• AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES
  申请人：BAZAN Guillermo C.

  公开号：US20120264649A1

  公开（公告）日：2012-10-18

  The invention provides molecules useful for enhancing charge transport across membranes, such as electron transport across membranes, and methods of using such molecules, for example in improving the performance of a microbial fuel cell or in staining microbes for observation. The amphiphilic molecule comprises a conjugated core with hydrophilic groups on either end. The amphiphilic molecule inserts into the membrane of a microbe and facilitates charge transfer across the membrane of the microbe.
• US3947471A
  申请人：——

  公开号：US3947471A

  公开（公告）日：1976-03-30
• US8614021B2
  申请人：——

  公开号：US8614021B2

  公开（公告）日：2013-12-24