N-hex-2-enyl-2,2-diphenyl-acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-hex-2-enyl-2,2-diphenyl-acetamide
• 英文别名: N-[(E)-hex-2-enyl]-2,2-diphenylacetamide
• 化学式: C₂₀H₂₃NO
• 分子量: 293.409
• InChiKey: YAODHXQAERYFHR-NYYWCZLTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS
  申请人：F. Hoffmann-La Roche AG

  公开号：EP1224163B1

  公开（公告）日：2005-03-30
• US6548522B1
  申请人：——

  公开号：US6548522B1

  公开（公告）日：2003-04-15
• US9428568B2
  申请人：——

  公开号：US9428568B2

  公开（公告）日：2016-08-30
• [EN] USE OF CARBONYLAMINO DERIVATIVES AGAINST CNS DISORDERS<br/>[FR] UTILISATION DE DERIVES CARBONYLAMINO CONTRE LES TROUBLES DU SYSTEME NERVEUX CENTRAL
  申请人：HOFFMANN LA ROCHE

  公开号：WO2001027070A1

  公开（公告）日：2001-04-19

  The present invention is concerned with the use of carbonylamino derivatives of general formula (I) wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF3; R1 signifies hydrogen or lower alkyl; R?2 and R3¿ signify, independently from each other, hydrogen, halogen or nitro; Y signifies CH or N; n is 0-6; m is 0-2; as well as with their pharmaceutically acceptable salts for the treatment of diseases, which relate to metabotropic glutamate receptor antagonists and/or agonists.
• [EN] CARBONYLAMINO DERIVATIVES USEFUL FOR OBTAINING IMMUNE REGULATION<br/>[FR] DERIVES CARBONYLAMINO PERMETTANT D'OBTENIR UNE IMMUNOREGULATION
  申请人：POSEIDON PHARMACEUTICALS AS

  公开号：WO2003004010A1

  公开（公告）日：2003-01-16

  The present invention relates to the use of a particular group of carbonylamino derivatives for the treatment or alleviation of diseases or conditions relating to immune regulation.