(2S,3S)-2-amino-3-[[3-[(4-hexoxybenzoyl)amino]phenyl]methoxy]butanedioic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2S,3S)-2-amino-3-[[3-[(4-hexoxybenzoyl)amino]phenyl]methoxy]butanedioic acid
• 化学式: C₂₄H₃₀N₂O₇
• 分子量: 458.5
• InChiKey: SLPRZRVSPFYCRT-SFTDATJTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  33
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  148
• 氢给体数：
  4
• 氢受体数：
  8

文献信息

• Beta-benzyloxyaspartate derivatives with amino group on benzene ring
  申请人：Shimamoto Keiko

  公开号：US20070238783A1

  公开（公告）日：2007-10-11

  L-threo-β-benzyloxyaspartate derivatives having a substituent on the benzene ring, represented by the following formula (1): wherein R is hydrogen, a linear or branched lower aliphatic acyl group with the acyl portion optionally substituted, an alicyclic acyl group, an aromatic acyl group with a substituent on the aromatic ring, an amino acid-derived group or a biotin derivative-derived group, having an amino substituent on the benzene ring, and salts thereof, which can easily bind to affinity column chromatography carriers as ligands of glutamate transporter proteins.

  具有苯环上取代基的L-单体-β-苄氧基天冬氨酸衍生物，化学式如下（1）：其中R为氢、具有酰基部分可选取代的线性或支链低级脂肪酰基、脂环酰基、苯环上具有取代基的芳香酰基、氨基酸衍生物基团或生物素衍生物基团，其在苯环上具有氨基取代基，以及其盐。该衍生物可以作为谷氨酸转运蛋白的配体，容易结合到亲和柱色谱载体上。
• B-BENZYLOXYASPARTATE DERIVATIVES WITH AMINO GROUP ON BENZENE RING
  申请人：SUNTORY LIMITED

  公开号：EP1397370A1

  公开（公告）日：2004-03-17
• BETA-BENZYLOXYASPARTATE DERIVATIVES WITH AMINO GROUP ON BENZENE RING
  申请人：Suntory Holdings Limited

  公开号：EP1397370B1

  公开（公告）日：2014-07-23
• Beta benzyloxyaspartate derivatives with amino group on benzene ring
  申请人：——

  公开号：US20040242652A1

  公开（公告）日：2004-12-02

  L-threo-&bgr;-benzyloxyaspartate derivatives having a substituent on the benzene ring, represented by the following formula (1): 1 wherein R is hydrogen, a linear or branched lower aliphatic acyl group with the acyl portion optionally substituted, an alicyclic acyl group, an aromatic acyl group with a substituent on the aromatic ring, an amino acid-derived group or a biotin derivative-derived group, having an amino substituent on the benzene ring, and salts thereof, which can easily bind to affinity column chromatography carriers as ligands of glutamate transporter proteins.
• US7247652B2
  申请人：——

  公开号：US7247652B2

  公开（公告）日：2007-07-24