(2,5-dioxopyrrolidin-1-yl) (4S)-4-cyano-4-[methyl(pyridin-4-yl)carbamothioyl]sulfanylpentanoate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (2,5-dioxopyrrolidin-1-yl) (4S)-4-cyano-4-[methyl(pyridin-4-yl)carbamothioyl]sulfanylpentanoate
• 化学式: C₁₇H₁₈N₄O₄S₂
• 分子量: 406.5
• InChiKey: DDFYYWVROUGVQD-KRWDZBQOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  161
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• PRODROGUES POLYMÈRES ET LEUR ADMINISTRATION SOUS-CUTANEE ET/OU INTRAMUSCULAIRE
  申请人：Centre National de la Recherche Scientifique

  公开号：EP3710061A1

  公开（公告）日：2020-09-23
• [EN] REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS<br/>[FR] RÉACTIONS ACTIVÉES PAR DES GELS THERMOSENSIBLES ET PHOTOSENSIBLES
  申请人：MASSACHUSETTS INST TECHNOLOGY

  公开号：WO2018140977A1

  公开（公告）日：2018-08-02

  Disclosed are methods, compositions, kits, and reagents to prepare compounds (e.g. polymers and small molecules) via radical reactions by utilizing thermoresponsive and photoresponsive gels. This invention discloses the preparation of polymers via controlled radical polymerizations from an iniferter or initiator, one or more reactant monomer, and a thermoresponsive and photoresponsive gel. Embodiments of the invention show that the polymerization is reversibly activated and/or deactivated by controlling one or more of the following external control stimuli: temperature, light, and catalyst presence. This invention also relates the preparation of Gel-PTH, a heterogeneous thermoresponsive and photoresponsive gel.