2-(1-benzothiophen-2-yl)-2-oxo-N-[2-[4-[(4-propan-2-ylphenyl)carbamothioylamino]phenyl]ethyl]acetamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(1-benzothiophen-2-yl)-2-oxo-N-[2-[4-[(4-propan-2-ylphenyl)carbamothioylamino]phenyl]ethyl]acetamide
• 化学式: C₂₈H₂₇N₃O₂S₂
• 分子量: 501.7
• InChiKey: ZLFHIAQNGKKPJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  35
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.18
• 拓扑面积：
  131
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Endoluminal medical device for local delivery of cathepsin inhibitors, method of making and treating
  申请人：Biggs P. David

  公开号：US20070293937A1

  公开（公告）日：2007-12-20

  An endoluminal medical device comprises a drug release system that releases a cathepsin inhibitor at a predetermined location within a lumen of a patient. The endoluminal devices and methods of treatment of disease can treat illnesses such as aneurysms and aortic dissections.