2-Chloro-2-hydroxy-2-phenylacetic acid

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Chloro-2-hydroxy-2-phenylacetic acid
• 化学式: C₈H₇ClO₃
• 分子量: 186.59
• InChiKey: UTNSTTZHNMPBEE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Method for expressing desxoyribonuclease in plants
  申请人：Philip Morris Products S.A.

  公开号：EP2468870A1

  公开（公告）日：2012-06-27

  The present invention provides, in one aspect, to a method for expressing DNase in a plant comprising growing a plant that has been transformed with a nucleic acid construct comprising a nucleic acid sequence encoding DNase under the control of a regulatory nucleotide sequence that regulates the transcription of said nucleic acid sequence in said plant.

  本发明的一个方面是提供了一种在植物中表达 DNase 的方法，该方法包括种植用核酸构建体转化的植物，该核酸构建体包含编码 DNase 的核酸序列，受调控核苷酸序列的控制，该核苷酸序列在所述植物中调控所述核酸序列的转录。
• Method for producing mullerian inhibitor substance in plants
  申请人：Philip Morris Products S.A.

  公开号：EP2468872A1

  公开（公告）日：2012-06-27

  The present invention provides, in one aspect, a method for producing Mullerian Inhibitor Substance in a plant comprising incubating or growing a plant into which has been introduced or infiltrated a nucleic acid construct comprising, consisting or consisting essentially of a nucleic acid sequence encoding a Mullerian Inhibitor Substance fusion protein that comprises a fusion protein partner that induces the formation of a protein body in a plant, preferably, wherein the step of introducing or infiltrating the plant is performed prior to the incubating or growing step.

  本发明在一个方面提供了一种在植物中生产苗勒氏抑制物质的方法，该方法包括孵育或生长植物，在该植物中导入或渗入核酸构建体，该核酸构建体由编码苗勒氏抑制物质融合蛋白的核酸序列组成，该融合蛋白包含可诱导植物形成蛋白体的融合蛋白伴侣，优选地，其中导入或渗入植物的步骤在孵育或生长步骤之前进行。
• Method for producing apolipoprotein in plants
  申请人：Philip Morris Products S.A.

  公开号：EP2468871A1

  公开（公告）日：2012-06-27

  The present invention provides, in one aspect, a method for producing Apolipoprotein in a plant comprising incubating or growing a plant into which has been introduced or infiltrated a nucleic acid construct comprising, consisting or consisting essentially of a nucleic acid sequence encoding an Apolipoprotein fusion protein that comprises a fusion protein partner that induces the formation of a protein body in a plant, preferably, wherein the step of introducing or infiltrating the plant is performed prior to the incubating or growing st ep.

  本发明在一个方面提供了一种在植物中生产载脂蛋白的方法，该方法包括孵育或培育植物，在该植物中引入或渗入核酸构建体，该核酸构建体由编码载脂蛋白融合蛋白的核酸序列组成或基本由编码载脂蛋白融合蛋白的核酸序列组成或基本由编码载脂蛋白融合蛋白的核酸序列组成，该载脂蛋白融合蛋白包含诱导在植物中形成蛋白体的融合蛋白伴侣，优选地，其中引入或渗入植物的步骤在孵育或培育st ep之前进行。
• Antibodies with decreased deamidation profiles
  申请人：MedImmune, LLC

  公开号：EP2703007A1

  公开（公告）日：2014-03-05

  A stable monoclonal antibody composition with a decreased deamidation profile, wherein the antibody comprises amino acid sequences that predispose the antibody to an elevated deamidation profile.

  一种脱酰胺谱降低的稳定的单克隆抗体组合物，其中抗体包含使抗体脱酰胺谱升高的氨基酸序列。
• OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS
  申请人：THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION

  公开号：EP0746551A1

  公开（公告）日：1996-12-11