Prop-2-enyl 4-methoxy-8-(phenylmethoxymethyl)-1-azabicyclo[3.3.1]non-3-ene-3-carboxylate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Prop-2-enyl 4-methoxy-8-(phenylmethoxymethyl)-1-azabicyclo[3.3.1]non-3-ene-3-carboxylate
• 化学式: C₂₁H₂₇NO₄
• 分子量: 357.4
• InChiKey: RAISAUCYDFHCTA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  48
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• [EN] AZA-BRIDGED BICYCLIC AMINE DERIVATIVES FOR USE AS NOVEL CHOLINERGIC RECEPTOR LIGANDS<br/>[FR] DERIVES D'AMINES BICYCLIQUES PONTEES AVEC AZA UTILISES EN TANT QUE NOUVEAUX LIGANDS DU RECEPTEUR CHOLINERGIQUE
  申请人：UNIV NORTH CAROLINA

  公开号：WO2004013143A2

  公开（公告）日：2004-02-12

  The present invention discloses novel cholinergic receptor ligands. The present invention also relates to novel compounds and the synthesis of such compounds as substituted derivatives of aza-bridged bicyclic amines for use as muscarinic receptor ligands. The present invention also relates to methods of regulating function of certain cholinergic receptors, and hence acting as antagonists, agonists and partial agonists at certain specific cholinergic receptor subtypes. The present invention also relates to methods for treating disorders associated with cholinergic receptors.