1,2-双(3-甲氧基-4-羟基苯基)乙烯 | 4957-27-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 中文名称: 1,2-双(3-甲氧基-4-羟基苯基)乙烯
• 英文名称: 4,4'-Dihydroxy-3,3'-dimethoxy-stilben
• 英文别名: 4,4'-Dihydroxy-3,3'-dimethoxy-stilbene；4-[2-(4-hydroxy-3-methoxyphenyl)ethenyl]-2-methoxyphenol
• CAS: 4957-27-1
• 化学式: C₁₆H₁₆O₄
• 分子量: 272.301
• InChiKey: KQPXJFAYGYIGRU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-双(3-甲氧基-4-羟基苯基)乙烯 生成 香草醛
  参考文献：
  名称：

  Pauly; Schanz, Chemische Berichte, 1923, vol. 56, p. 982

  摘要：

  DOI：
• 作为产物：
  描述：

  异丁香酚 在 RuCl2(1,3-dimesityl-imidazolidin-2-yl)(PCy3)(=CHPh) 作用下， 生成 1,2-双(3-甲氧基-4-羟基苯基)乙烯
  参考文献：
  名称：

  原子分散钯驱动木质纤维素还原催化分馏成烯烃官能化苯酚

  摘要：

  由于木质素是自然界中唯一可再生的芳香族有机资源，因此寻找有效的木质素解聚催化剂以高产率和高选择性生产官能化苯酚非常重要但具有挑战性。在此，我们报道了一种锚定在碳载体（Pd/ZnO/C）上的极低负载和原子分散的钯催化剂，用于木质纤维素的还原催化分馏（RCF），其中接近理论最大芳香族单体产率（40.7 wt％） ，实现了对 4- n-丙烯基取代酚（62 mol%）的良好选择性，以及对纤维素和半纤维素（92 和 70 wt%）的高保留。计算得出的周转数 (TON)（375 mol芳烃mol Pd –1）比商用 Pd/C 催化剂高 46 倍。Pd/ZnO/C催化剂在回收RCF实验中具有稳定性和可重复使用性。基于对一系列木质素模型化合物的详细研究，提出了当前催化体系的合理反应途径。以Pd/ZnO/C催化的杉木RCF中的4-正丙烯基愈创木酚为底物，实现了对称单体二苯乙烯（天然产物）的制备。该研究为低成

  DOI：

  10.1021/acscatal.3c05461

文献信息

• GOLD-CATALYSED PROCESS FOR MANUFACTURING CHROMENES INTENDED FOR THE PREPARATION OF THERMOSETTING RESINS
  申请人：ARIANEGROUP SAS

  公开号：US20210024534A1

  公开（公告）日：2021-01-28

  A process for manufacturing chromenes intended for the preparation of thermosetting resins, includes transforming an aromatic propargyl ether of general formula (I) into a chromene by homogeneous gold(I) catalysis with the catalyst (acetonitrile)[(2-biphenyl)di-tert-butylphosphine]gold(I) hexafluoroantimonate in an organic solvent under an inert or non-inert atmosphere. Moreover, a process for preparing a material made of thermoset resin, includes successively a) implementation of the above process; polymerization of the reaction product obtained in step a) so as to obtain the material made of thermoset resin; c) recovery of the material made of thermoset resin obtained in step b).

  一种用于制备用于制备热固性树脂的噻吩的工艺，包括将一般式(I)的芳香丙炔醚通过均相金(I)催化剂与催化剂(乙腈)[(2-联苯)二叔丁基膦]金(I)六氟安替酸盐在有机溶剂中在惰性或非惰性气氛下转化为噻吩。此外，一种制备热固性树脂材料的工艺，包括依次进行a) 实施上述工艺；聚合步骤a)中获得的反应产物以获得制备热固性树脂的材料；c) 回收步骤b)中获得的制备热固性树脂材料。
• PROCESS FOR PRODUCING CHROMENES BY CATALYSIS WITH COPPER SALTS INTENDED FOR THE PREPARATION OF THERMOSETTING RESINS
  申请人：ARIANEGROUP SAS

  公开号：US20210024535A1

  公开（公告）日：2021-01-28

  A process for producing chromenes intended for the preparation of thermosetting resins, includes converting an aromatic propargyl ether of general formula (I) into a chromene by homogeneous catalysis with copper salts in anisole at a temperature between 100 and 170° C. Moreover, a process for preparing a material made of thermoset resin, includes successively a) carrying out the above process; b) polymerizing the reaction product obtained in a) so as to obtain the material made of thermoset resin; c) recovering the material made of thermoset resin obtained in b).

  生产用于制备热固性树脂的咔喷啉的方法包括将一般式(I)的芳香丙炔醚通过在苯甲醚中与铜盐进行均相催化，在100至170°C的温度下转化为咔喷啉。此外，制备热固性树脂材料的方法包括依次进行以下步骤：a) 执行上述过程；b) 聚合步骤a)中得到的反应产物，以获得热固性树脂材料；c) 回收步骤b)中获得的热固性树脂材料。
• Cloning, Expression, and Sequence Analysis of a Lignostilbene-<i>α,β</i>-dioxygenase Gene from<i>Pseudomonas paucimobilis</i>TMY1009
  作者：Shigehiro Kamoda、Yoshimasa Saburi

  DOI：10.1271/bbb.57.926

  日期：1993.1

  From the genomic library of Pseudomonas paucimohilis TMYl009 constructed with the cosmid pHC79, an 8-kb BamHI-KpnI fragment encoding Iignostilbene-α,β-dioxygenase (LSD) was cloned into pUC19 (designated pKSN2510). E. coli JM109 having pKSN2510 produced a small amount of LSD only when the lac promoter was induced by isopropyl-β-D-thio-galactopyranoside (IPTG). The 1.9-kb SalI fragment containing the LSD gene on pKSN2510 was subcloned into pUCl19 in opposite directions (designated pKHN2560 and pKHN2590). The LSD gene on pKHN2590 was expressed in E. coli MV1184 using the lac promoter.LSD produced by E. coli MV1184 transformed with pKHN2590 (cloned LSD) was purified and found to be identical with LSD-I, which was the major isozyme produced by P. paucimobilis TMY1009. Cloned 1.9-kb nucleotide was sequenced and one open reading frame composed to 486 codons was found.

  从用cosmid pHC79构建的假单胞菌paucimohilis TMYl009基因组文库中，将一个8kb的BamHI-KpnI片段克隆到pUC19（命名为pKSN2510）中，该片段编码Iignostilbene-α,β-dioxygenase（LSD）。只有当异丙基-β-D-硫代-半乳糖苷（IPTG）诱导lac启动子时，携带pKSN2510的E. coli JM109才会产生少量的LSD。将pKSN2510上包含LSD基因的1.9kb SalI片段以相反方向亚克隆到pUCl19中（命名为pKHN2560和pKHN2590）。使用lac启动子在E. coli MV1184中表达pKHN2590上的LSD基因。对转化了pKHN2590（克隆的LSD）的E. coli MV1184产生的LSD进行纯化，发现其与LSD-I相同，后者是假单胞菌paucimohilis TMY1009产生的主要同工酶。对克隆的1.9kb核苷酸进行测序，发现一个由486个
• Structural and Enzymatical Comparison of Lignostilbene-<i>α,β</i>-dioxygenase Isozymes, I, II, and III, from<i>Pseudomonas paucimobilis</i>TMY1009
  作者：Shigehiro Kamoda、Yoshimasa Saburi

  DOI：10.1271/bbb.57.931

  日期：1993.1

  Three isozymes of lignostilbene-alpha,beta-dioxygenase (LSD) from Pseudomonas paucimobilis TMY1009 were separated on QAE-Toyopearl chromatography. All active fractions were further chromatographed on DEAE-Toyopearl, Butyl-Toyopearl, and Sephacryl S-300 columns. Then the isozymes I, II, and III were purified homogeneously. All three isozymes consisted of two subunits with the same mol. mass. According

  在QAE-Toyopearl色谱上分离了来自假单胞菌TMY1009的三种木质素-α，β-双加氧酶（LSD）同工酶。所有活性级分均在DEAE-Toyopearl，Butyl-Toyopearl和Sephacryl S-300柱上进行色谱分离。然后将同工酶I，II和III均匀纯化。所有三个同工酶均由具有相同摩尔的两个亚基组成。质量 根据这三个同工酶的N末端氨基酸序列最多25个残基以及肽酶消化的反相HPLC图谱，发现LSD-1，II和III分别由α-α，α-β，和βbeta亚基。他们对二苯乙烯和苯乙烯衍生物的几种底物显示出不同的特异性。
• Nutriprotective diet
  申请人：Potvin Steeves

  公开号：US10092614B2

  公开（公告）日：2018-10-09

  The present document describes a nutriprotective diet comprising a nutriprotective amount of a sugar plant syrup, a sugar plant syrup extract, a sugar plant extract, or combinations thereof The present document also describes a method of eliciting a nutriprotective effect in a subject, which comprises administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document also describes a method of treating a subject with a disorder, by administering a nutriprotective amount of a nutriprotective diet according to the present invention. Also, the present document describes a process for the extraction of polyphenolic compounds from maple syrup using adsorbent materials, and the extracts obtained therefrom.

  本文件描述了一种营养保护性膳食，其中包含一定量的营养保护性糖类植物糖浆、糖类植物糖浆提取物、糖类植物提取物或其组合。 本文件还描述了一种在受试者中激发营养保护作用的方法，其中包括施用一定量的根据本发明的营养保护性膳食。此外，本文还描述了一种通过施用一定量的根据本发明的营养保护性饮食来治疗患有疾病的受试者的方法。此外，本文还描述了一种利用吸附材料从枫糖浆中提取多酚化合物的工艺，以及从中获得的提取物。