1,3,4,5-四氢-5-乙酰基-4-苯基-1-(苯基甲基)-2H-1,5-苯并重氮基庚英-2-酮 | 105201-46-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 1,3,4,5-四氢-5-乙酰基-4-苯基-1-(苯基甲基)-2H-1,5-苯并重氮基庚英-2-酮
• 英文名称: N-[(E)-[(2E,4E)-undeca-2,4-dienylidene]amino]nitrous amide
• CAS: 105201-46-5
• 化学式: C₁₁H₁₉N₃O
• 分子量: 209.29
• InChiKey: ZEPDNBQRELJMRH-SNUJAXHWSA-N

物化性质

• 沸点：
  302.1±25.0 °C(Predicted)
• 密度：
  0.95±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  15
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  53.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• INHIBITORS OF LONG AND VERY LONG CHAIN FATTY ACID METABOLISM AS BROAD SPECTRUM ANTI-VIRALS
  申请人：Koyuncu Emre

  公开号：US20130190381A1

  公开（公告）日：2013-07-25

  The present invention provides methods and compounds for treating viral infections using modulators of host cell enzymes relating to long chain fatty acid and lipid droplet metabolism. It includes a method of treating viral infections using triacsin C and its relatives, analogues and derivatives as well as other inhibitors of long chain fatty acid metabolism and lipid droplet metabolism.
• ANTI-VIRAL COMBINATION THERAPY
  申请人：KOYUNCU Emre

  公开号：US20150139949A1

  公开（公告）日：2015-05-21

  The present invention provides methods and compounds for treating viral infections using combinations modulators of an HCV-associated component and modulators of host cell enzymes. The present invention also provides methods and compounds for treating viral infections using combinations of modulators of host cell enzymes and other agents that work, at least in part by modulating hos factors.
• US9168269B2
  申请人：——

  公开号：US9168269B2

  公开（公告）日：2015-10-27