1,4-二异氰酸基-4-甲基戊烷 | 112147-61-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 1,4-二异氰酸基-4-甲基戊烷
• 英文名称: 1,4-diisocyanato-4-methyl-pentane
• 英文别名: 1,4-diisocyanato-4-methylpentane；DIMP
• CAS: 112147-61-2
• 化学式: C₈H₁₂N₂O₂
• 分子量: 168.195
• InChiKey: PFJZOBRGDTYDQC-UHFFFAOYSA-N

物化性质

• 沸点：
  101-103 °C(Press: 13 Torr)
• 密度：
  0.99±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  58.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4-二异氰酸基-4-甲基戊烷 、 N-乙基-N-羟乙基苯胺 反应 18.0h， 生成 2-(ethyl(phenyl)amino)ethyl 4-isocyanato-4-methylpentylcarbamate
  参考文献：
  名称：

  Alternative Route to the Diisocyanate Building Block 1,4-Diisocyanato-4-methylpentane (DIMP)

  摘要：

  The synthesis of 1,4-diisocyanato-4-methylpentane was accomplished starting from isobutyronitrile in six steps with 53% overall yield. The two isocyanates were installed by a double Curtius rearrangement. The product reacts with alcohol in a regioselective manner.

  DOI：

  10.1080/00397910903097278
• 作为产物：
  描述：

  2,2-dimethyladipoyl diazide 以 1,2-二氯乙烷 为溶剂， 反应 1.0h， 以10.4 g的产率得到1,4-二异氰酸基-4-甲基戊烷
  参考文献：
  名称：

  Alternative Route to the Diisocyanate Building Block 1,4-Diisocyanato-4-methylpentane (DIMP)

  摘要：

  The synthesis of 1,4-diisocyanato-4-methylpentane was accomplished starting from isobutyronitrile in six steps with 53% overall yield. The two isocyanates were installed by a double Curtius rearrangement. The product reacts with alcohol in a regioselective manner.

  DOI：

  10.1080/00397910903097278

文献信息

• COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS
  申请人：Chodorowski-Kimmes Sandrine

  公开号：US20100239509A1

  公开（公告）日：2010-09-23

  The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups; of a monocarboxylic acid containing 6 to 32 carbon atoms; of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and (b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

  本专利申请涉及一种化妆品或皮肤科学组合物，包括在化妆品或皮肤科学上可接受的介质中，包含以下聚合物的组合物：(a) 由以下反应得到的聚合物骨架：含有3至6个羟基的多元醇；含有6至32个碳原子的一元羧酸；至少含有两个羧基COOH的多元羧酸，和/或类似多元羧酸的环酐和/或至少含有一个羧基COOH的内酯；以及(b) 至少一个连接到所述聚合物骨架的连接基团，并能够与一个或多个配对连接基团建立H键，每个连接基团的配对涉及至少三个H（氢）键。该专利申请还涉及使用所述组合物的化妆品处理过程。
• [EN] MONOMERS CAPABLE OF FORMING FOUR HYDROGEN BRIDGES AND SUPRAMOLECULAR POLYMERS FORMED BY COPOLYMERIZATION OF THESE MONOMERS WITH REGULAR MONOMERS<br/>[FR] MONOMERES POUVANT FORMER QUATRE LIAISONS HYDROGENE ET POLYMERES SUPRAMOLECULAIRES FORMES PAR COPOLYMERISATION DE CES MONOMERES AVEC DES MONOMERES REGULIERS
  申请人：SUPRAPOLIX BV

  公开号：WO2004016598A1

  公开（公告）日：2004-02-26

  The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).

  该发明涉及通过共聚合含有四重氢键结合基团的单体与一个或多个选择的单体，合成含有自互补四重氢基团的聚合物。由于聚合物链之间存在基于多重氢键相互作用（超分子相互作用）的额外物理相互作用，所得到的聚合物表现出独特的新特性。
• Preparation of supramolecular polymers by copolymerization of monomers containing quadruple hydrogen bonding units with regular monomers
  申请人：——

  公开号：US20040034190A1

  公开（公告）日：2004-02-19

  The invention relates to the synthesis of polymers containing self-complementary quadruple hydrogen groups by copolymerizing monomers containing a quadruple hydrogen bonding group with one or more monomers of choice. The resulting polymers show unique new characteristics due to the presence of additional physical interactions between the polymer chains that are based on multiple hydrogen bonding interactions (supramolecular interactions).

  该发明涉及通过共聚合含有四重氢键结合基团的单体与一个或多个选择单体，合成含有自互补四重氢键基团的聚合物。由于聚合物链之间存在基于多重氢键作用（超分子相互作用）的额外物理相互作用，所得到的聚合物表现出独特的新特性。
• FUNCTIONALIZED HIGHLY BRANCHED MELAMINE-POLYAMINE POLYMERS
  申请人：Peretolchin Maxim

  公开号：US20120252987A1

  公开（公告）日：2012-10-04

  The present invention relates to a method for producing amphiphilic functionalized highly branched melamine-polyamine polymers by condensing melamine and optionally a melamine derivate having at least one different amine having at least two primary amino groups and optionally also with urea and/or at least one urea derivative and/or with at least one at least difunctional diisocyanate or polyisocyanate and/or at least one carbolic acid having at least two carboxyl groups or at least one derivative thereof, optionally quaternizing a portion of the amino groups of the polymer thereby obtained, reacting the polymer thus obtained with at least one compound capable of undergoing a condensation or addition reaction with amino groups, and optionally quaternizing at least part of the amino groups of the polymer obtained in the first step. The invention further relates to the amphiphilic functionalized highly branched melamine-polyamine polymers that can be obtained by the method according to the invention, and to the use thereof as surface active agents.

  本发明涉及一种通过将三聚氰胺和至少一种具有至少两个主要氨基的不同氨基的三聚氰胺衍生物以及可能还包括尿素和/或至少一种尿素衍生物和/或至少一种至少双官能团二异氰酸酯或多异氰酸酯和/或至少一种至少具有两个羧基的羧酸或其衍生物缩合，从而制备含有两性功能化的高支化三聚氰胺-多胺聚合物的方法。可选地，对所获得的聚合物的部分氨基进行季铵化，然后将所获得的聚合物与至少一种能够与氨基发生缩合或加成反应的化合物反应，并可选地对第一步中获得的聚合物的部分氨基进行季铵化。本发明还涉及通过本发明的方法可以获得的含有两性功能化的高支化三聚氰胺-多胺聚合物，以及将其用作表面活性剂的用途。
• COSMETIC TREATMENT PROCESSES AND KIT
  申请人：Dublanchet Anne-Claude

  公开号：US20140155352A1

  公开（公告）日：2014-06-05

  The present invention relates to a cosmetic process for treating keratin materials, which can give them, especially in a long-lasting and reversible manner, interesting cosmetic properties; this process comprising the application to said materials: in a first stage, of a cosmetic composition comprising at least one graftable species, comprising at least one unit of formula (Ia): and in a second stage, of a cosmetic composition comprising at least one cosmetic active agent bearing at least one unit of formula (Ia): The invention also relates to a kit comprising said compositions.

  本发明涉及一种用于处理角蛋白材料的化妆品工艺，可以在长期和可逆的情况下赋予它们有趣的化妆品特性；该工艺包括向所述材料施加以下组成部分的应用：第一阶段，包括至少一种可接枝的物种的化妆品组合物，其中包括至少一个式(Ia)的单元；第二阶段，包括至少一种具有至少一个式(Ia)的化妆品活性剂的化妆品组合物：本发明还涉及包括所述组合物的套件。