1-(1-甲基-6H-吡啶-3-基)乙酮 | 100281-01-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 1-(1-甲基-6H-吡啶-3-基)乙酮
• 英文名称: 1-(1-Methyl-1,6-dihydro-pyridin-3-yl)-ethanone
• 英文别名: Ethanone, 1-(1,6-dihydro-1-methyl-3-pyridinyl)-(9CI)；1-(1-methyl-2H-pyridin-5-yl)ethanone
• CAS: 100281-01-4
• 化学式: C₈H₁₁NO
• 分子量: 137.181
• InChiKey: YUDYIGCCMNPJLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-acetyl-1-methylpyridinium iodide 以40%的产率得到
  参考文献：
  名称：

  BARTON, D. H. R.;FEKIH, ABDELWAHEB;LUSINCHI, XAVIER, TETRAHEDRON LETT., 1985, 26, N 31, 3693-3696

  摘要：

  DOI：

文献信息

• Selective reduction of imonium salts by sodium hydrogen telluride
  作者：Derek H.R. Barton、Abdelwaheb Fekih、Xavier Lusinchi

  DOI：10.1016/s0040-4039(00)89225-4

  日期：1985.1
• THE USE OF N-METHYL PYRIDINIUM DERIVATIVES FOR HEPATOPROTECTION
  申请人：Hependo Sp. z.o.o.

  公开号：EP2124946B1

  公开（公告）日：2012-05-23
• NICOTINAMIDE COMPOSITIONS FOR TREATMENT OF SKIN DISEASES AND DISORDERS
  申请人：Gebicki Jerzy

  公开号：US20080112968A1

  公开（公告）日：2008-05-15

  The present invention is directed to compositions of nicotinamide derivatives combined with wakame seaweed, wakame extracts, or glycosaminoglycans, and their use in treating skin diseases and disorders.
• Use of Quaternary Pyridinium Compounds for Vasoprotection and/or Hepatoprotection
  申请人：MARCINEK Andrzej

  公开号：US20110118316A1

  公开（公告）日：2011-05-19

  The invention relates to a method for the treatment or prevention of diseases or conditions associated with vascular endothelium dysfunction or liver injury comprising the administration to a patient in a need of such treatment or prevention of a therapeutically or prophylactically effective amount of a compound selected from the group consisting of: wherein R represents hydrogen atom, CH 3 , OH, pyridyl (C 5 H 4 N), 1-methylpyridyl (C 5 H 4 N—CH 3 ) or pyridyl substituted with hydroxy group ((OH)C 5 H 3 N), and X represents a physiologically acceptable counterion.
• US7893095B2
  申请人：——

  公开号：US7893095B2

  公开（公告）日：2011-02-22