methyl 4-{(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: methyl 4-{(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl}benzoate
• 英文别名: methyl 4-[(4Z)-4-[(5-nitrofuran-2-yl)methylidene]-3,5-dioxopyrazolidin-1-yl]benzoate
• 化学式: C16H11N3O7
• 分子量: 357.27
• InChiKey: LKIUMJGOPZJJLT-WQLSENKSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  26
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  135
• 氢给体数：
  1
• 氢受体数：
  7

文献信息

• Inhibitors of ubiquitin E1
  申请人：Weissman Allan M.

  公开号：US20080306130A1

  公开（公告）日：2008-12-11

  The present invention features pyrazolidinyl compounds, pharmaceutical compositions of substituted pyrazolidinyl compounds and methods of treating a patient suffering from cancer or viral infection, the method comprising administering to a patient one or more pyrazolidinyl compounds of the invention.
• INHIBITORS OF UBIQUITIN E1
  申请人：Weissman Allan M.

  公开号：US20100305180A1

  公开（公告）日：2010-12-02

  The present invention features pyrazolidinyl compounds, pharmaceutical compositions of substituted pyrazolidinyl compounds and methods of treating a patient suffering from cancer or viral infection, the method comprising administering to a patient one or more pyrazolidinyl compounds of the invention.
• US8242160B2
  申请人：——

  公开号：US8242160B2

  公开（公告）日：2012-08-14