2,4-Dimethyl-6-(methylthio)pyridine

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2,4-Dimethyl-6-(methylthio)pyridine
• 英文别名: 2,4-dimethyl-6-methylsulfanylpyridine
• 化学式: C₈H₁₁NS
• 分子量: 153.25
• InChiKey: VIXVYPWINNHLTO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  38.2
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• HETEROCYCLIC COMPOUND
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP3287454A1

  公开（公告）日：2018-02-28

  The present invention provide a compound having an orexin receptor antagonistic activity, which is expected to be useful as medicaments such as agents for the prophylaxis or treatment of sleep disorder, depression, anxiety disorder, panic disorder, schizophrenia, drug dependence, Alzheimer's disease and the like. The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.

  本发明提供了一种具有奥曲肽受体拮抗活性的化合物，该化合物有望用作药物，如预防或治疗睡眠障碍、抑郁症、焦虑症、恐慌症、精神分裂症、药物依赖、阿尔茨海默病等的药物。 本发明涉及一种由式（I）代表的化合物： 其中各符号如说明书中所定义，或其盐。
• ORGANIC MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME
  申请人：Luminescence Technology Corp.

  公开号：EP3040395B1

  公开（公告）日：2017-10-18
• SUBSTITUTED TRIAZINE BMI-1 INHIBITORS
  申请人：PTC THERAPEUTICS, INC.

  公开号：US20160297798A1

  公开（公告）日：2016-10-13

  Amine substituted triazine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein.
• US9975878B2
  申请人：——

  公开号：US9975878B2

  公开（公告）日：2018-05-22