(2S,5R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酰胺类
• 英文名称: (2S,5R)-3,3-dimethyl-6-[(5-methyl-3-phenyl-1,2-oxazole-4-carbonyl)amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 化学式: C₁₉H₁₉N₃O₅S
• 分子量: 401.4
• InChiKey: UWYHMGVUTGAWSP-XLGXCUCASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  138
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• TOPISCH ANWENDBARE MITTEL GEGEN NAGELPILZERKRANKUNGEN
  申请人：BioEqual AG

  公开号：EP1143950B1

  公开（公告）日：2005-03-09
• PHARMAZEUTISCHE UND KOSMETISCHE FORMULIERUNGEN ZUR BEHANDLUNG DER NÄGEL
  申请人：BioEqual AG

  公开号：EP1680076A1

  公开（公告）日：2006-07-19
• Pharmaceutical and cosmetic formulations for treating fingernails
  申请人：Meyer Hans

  公开号：US20070166249A1

  公开（公告）日：2007-07-19

  Topically applicable agents are described, for the treatment of nail diseases and for nail care, which contain where needed, besides one or more active substance and physiologically compatible active ingredient and solution mediator, one or more compounds of the formula I R—O—R 1 (I) where R represents a straight or branched alkyl residue with 5-8 carbon atoms and R 1 represents a formyl group or an acetyl group
• MATERIALS AND METHODS FOR THE DETECTION OF TRACE AMOUNTS OF SUBSTANCES IN BIOLOGICAL AND ENVIRONMENTAL SAMPLES
  申请人：KABIR Abuzar

  公开号：US20180059082A1

  公开（公告）日：2018-03-01

  The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.
• US6740326B1
  申请人：——

  公开号：US6740326B1

  公开（公告）日：2004-05-25