1-[(2R,5S)-3-叠氮基-5-(羟基甲基)四氢呋喃-2-基]-5-甲基嘧啶-2,4-二酮 | 126543-51-9

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 中文名称: 1-[(2R,5S)-3-叠氮基-5-(羟基甲基)四氢呋喃-2-基]-5-甲基嘧啶-2,4-二酮
• 中文别名: 苯并呋喃,2,3-二氢-2-(1-甲基乙基)-,(R)-(9CI)
• 英文名称: 1-[(2R,5S)-3-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• CAS: 126543-51-9
• 化学式: C10H13N5O4
• 分子量: 267.24
• InChiKey: GRAIAQOAALQBTB-JFOAVASISA-N

物化性质

• 熔点：
  167-169 °C

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  93.2
• 氢给体数：
  2
• 氢受体数：
  6

文献信息

• Method of assessing levels of infectious virus in a biological sample
  申请人：——

  公开号：US20030003446A1

  公开（公告）日：2003-01-02

  Disclosed is a method for identifying levels of an infectious virus in a cell population by comparing the level of a viral gene product in a first population of cells cultured in the presence of the virus with the level of the viral gene product in a second population of cells cultured under conditions that inhibit replication of the virus, e.g., cells that are cultured in the presence of an inhibitor of replication of the virus.

  本发明公开了一种用于鉴定细胞群中传染性病毒水平的方法，该方法通过比较在病毒存在的情况下培养的第一细胞群中病毒基因产物的水平与在抑制病毒复制的条件下培养的第二细胞群（例如在病毒复制抑制剂存在的情况下培养的细胞）中病毒基因产物的水平。
• [EN] METHOD OF ASSESSING LEVELS OF INFECTIOUS VIRUS IN A BIOLOGICAL SAMPLE<br/>[FR] PROCEDE D'EVALUATION DE TAUX DE VIRUS INFECTIEUX DANS UN ECHANTILLON BIOLOGIQUE
  申请人：VI TECHNOLOGIES INC

  公开号：WO2002099073A2

  公开（公告）日：2002-12-12

  Disclosed is a method for identifying levels of an infectious virus in a cell population by comparing the level of a viral gene product in a first population of cells cultured in the presence of the virus with the level of the viral gene product in a second population of cells cultured under conditions that inhibit replication of the virus, e.g., cells that are cultured in the presence of an inhibitor of replication of the virus.